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Squamous Cell Carcinoma

Squamous cell carcinoma

Juga dikenal sebagai: SCC, Solar-induced squamous cell carcinoma, Multifocal squamous cell carcinoma in situ, Bowen's disease

Ditinjau dokter hewanBirdCatDogTurtleUrgensi: ModerateSeberapa umum: Common

Singkatnya

Squamous cell carcinoma (SCC) is a common, sun-induced skin and oral cancer in dogs and cats, also occasionally affecting birds and turtles. Learn about symptoms, diagnosis, and treatment options.

An older white cat with early solar-induced crusting and redness on its ear tips.
Older cats with white or lightly pigmented ears are highly susceptible to solar-induced squamous cell carcinoma.

TL;DR. Kanker kulit dan mulut umum terkait matahari; deteksi dini dan pengobatan lokal agresif penting.

Kucing tua dengan telinga putih atau pigmentasi terang berisiko tinggi SCC surya.

Apa itu?

Tumor ganas keratinosit kulit dan mukosa. Bentuk kutan (ulkus merusak yang tidak sembuh) dan oral (sangat invasif, sering erosi tulang). Terutama anjing dan kucing; burung dan kura-kura mungkin.

Penyebab dan faktor risiko

UV kronis: faktor kutan utama. Risiko: bulu putih, kulit terang, bulu jarang, ketinggian, matahari kuat. Pada kucing, papillomavirus mungkin berperan.

"One paper suggests a papillomavirus may be involved in the etiology of feline squamous cell carcinoma. Older, white cats or those with lightly pigmented noses and that live in sunny climates are at risk. Lesions progress slowly through early solar damage with crusting and erythema to carcinoma in situ to invasive squamous cell carcinoma."

"Sunlightinduced tumors on the flank and ventrum occur most commonly in lightly pigmented dog breeds such as Dalmatians, Beagles, Whippets, and White English Bull terriers. The condition is common in cats, with highest incidence reported in older white cats."

Tanda yang perlu diwaspadai

Kulit: kerak di telinga/hidung/kelopak/perut; eritema; ulkus tak sembuh; massa seperti kutil.

Mulut: disfagia, anoreksia, napas bau, perdarahan.

Jari: jari bengkak nyeri; kuku cacat atau hilang tanpa trauma.

A dog's belly showing red, crusty skin lesions caused by sun exposure.
Lesi surya perut pada anjing dapat berkembang menjadi SCC invasif.

Diagnosis

Pemeriksaan kulit, mulut, dan kelenjar getah bening. Sitologi sering tidak definitif. Biopsi dengan histopatologi: standar emas. Staging: aspirasi kelenjar, X-ray toraks 3 proyeksi, CT tumor oral.

A digital X-ray screen showing a canine chest radiograph used for cancer staging.
X-ray toraks 3 proyeksi untuk metastasis paru.

Pengobatan

Bedah: pilihan utama dengan margin luas (pinnektomi, amputasi jari; oral: mandibulektomi/maksilektomi parsial).

Radioterapi ± hipertermia jika reseksi tidak lengkap.

Medis: Carboplatin, Cisplatin; Piroxicam paliatif.

"Radiotherapy plus hyperthermia has been successful"

Prognosis

SCC kutan awal dioperasi: baik hingga sangat baik. SCC oral, terutama kucing: waspada hingga buruk. Eksotik: data terbatas.

Pencegahan

  • Hindari matahari 10:00-16:00
  • Tabir surya khusus hewan saja
  • Film UV
  • Periksa kulit dan mulut secara rutin

Kapan menghubungi dokter hewan

Darurat: perdarahan mulut berat, disfagia mendadak, penurunan berat cepat, nyeri ekstrem.

Untuk ras tertentu

Kulit terang atau bulu jarang:

Sumber

  • Small-Animal Dermatology: A Color Atlas and Therapeutic Guide, pages 441, 444.
  • Cowell and Tyler's Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition, page 153.
  • Current Techniques in Small Animal Surgery, 5th Edition, page 392.
  • Textbook of Veterinary Internal Medicine, 5th Edition, page 464.

My highlights & notes

Tanda & gejala

Ras berisiko lebih tinggi

Cara didiagnosis

  • Biopsy with histopathologic examinationStandar emas
  • CT scan
  • Cytology
  • Regional lymph node aspirate
  • Three-view thoracic radiographs

Pendekatan pengobatan

Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.

Pertanyaan umum

What is Squamous Cell Carcinoma?

Squamous cell carcinoma (SCC) is a common, sun-induced skin and oral cancer in dogs and cats, also occasionally affecting birds and turtles. Learn about symptoms, diagnosis, and treatment options.

What are the symptoms of Squamous Cell Carcinoma?

Loss of appetite、Bleeding、Crusting、Trouble swallowing (dysphagia)、Skin redness、Bad breath、Proliferative skin lesions、Ulcerative skin lesions

How is Squamous Cell Carcinoma diagnosed?

Biopsy with histopathologic examination、CT scan、Cytology、Regional lymph node aspirate、Three-view thoracic radiographs

How is Squamous Cell Carcinoma treated?

Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.

Sumber

  1. 2016 oncology guidelines
  2. 皮膚病 教科書點子書 Small-Animal-Dermatology-A-Color-Atlas-and-Therapeutic-Guide · p. 444
  3. Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 153
  4. Current Techniques in Small Animal Surgery, 5th Edition (VetBooks.ir) · p. 392
  5. 皮膚病 教科書點子書 Small-Animal-Dermatology-A-Color-Atlas-and-Therapeutic-Guide · p. 441
  6. Internal Medicine 5th · p. 464

Artikel ini edukasi umum, bukan pengganti saran dokter hewan. Jika hewan sakit, konsultasikan dokter hewan.

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