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Lymphoma

Lymphosarcoma

Även känd som: Malignant lymphoma, Lymphosarcoma

VeterinärgranskadCatDogBrådska: ModerateHur vanligt: Common

Kort sagt

Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.

Anatomical diagram of a dog's lymphatic system showing major lymph nodes.
Lymphoma often first presents as painless swelling in the peripheral lymph nodes, which are distributed throughout your pet's body.

TL;DR. Vanlig lymfocytcancer i solida organ; ofta svullna lymfknutor eller kroniska mag-tarmproblem; svarar val pa cytostatika.

Ofta smärtfri svullnad av perifera lymfknutor.

Vad ar det?

Malign lymfocytsjukdom fran solida organ (lymfknutor, lever, mjalte, oga), skiljd fran lymfoid leukemi fran benmargen. Former: multicentrisk (hund vanlig), alimentär (katt vanlig), mediastinal, extranodal (hud, oga, njure, CNS).

Orsaker och riskfaktorer

Multifaktoriell. Katt: FeLV/FIV-koppling. Miljo (rok, bekämpningsmedel) misstankt. Medelalders till aldre.

Tecken

  • Lymfadenopati (kardinal, multicentrisk)
  • Letargi, dyspne/hosta, viktnedgang, anorexi, krakningar/diarre (vanliga)
  • PU/PD (hyperkalcemi), ogon-/hudforandringar, nysningar, neurotecken (ibland)

Close-up of a cat's eye showing cloudiness and redness from anterior uveitis.
Okulara forandringar som uveit kan folja med.

Diagnostik

FNA-cytologi, biopsi (guldstandard), ultraljud (tarmvagg), staging (blodstatus, kemi, FeLV/FIV, rontgen/UL), immunfenotyp (flow/PARR).

Ultrasound monitor showing a thickened intestinal wall in a cat.
Ultraljud visar typisk tarmvaggsfortjockning vid alimentärt lymfom.

Behandling

Systemiskt: multiagent CHOP/CEOP (referens); COP Protocol som alternativ; rescue Lomustine, Cytarabine (CNS). Mal: livskvalitet och remission.

Prognos

Obehandlad: ~4–8 veckor. Hund CHOP: ~80–90% remission, ~12–16 manader. Katt CHOP: ~65–75%, ~6–9 manader. Small-cell intestinal (katt): ofta >2 ar.

Forebyggande

Katt: inomhus, FeLV-skydd. Mindre rok/bekämpningsmedel. Kontroller av seniors.

Nar du ska ringa veterinaren

Akut: andnod, plotslig blindhet, kollaps, kvarstaende krakningar/diarre, ansiktsödem, feber/hypotermi.

Kallor

  • Small Animal Internal Medicine, 5th Edition, pages 1192, 1194, 1198, 1200.

My highlights & notes

Tecken & symptom

Raser med högre risk

Hur det diagnostiseras

  • Histopathologic EvaluationGuldstandard
  • Advanced imaging (CT or MRI)
  • CBC, serum biochemistry profile, and urinalysis
  • Cerebrospinal fluid (CSF) analysis
  • FeLV and FIV testing
  • Fine-needle aspiration (FNA) with cytologic evaluation
  • Flow cytometry
  • Immunohistochemistry
  • Polymerase chain reaction for antigen receptor rearrangement (PARR)
  • Positive contrast-enhanced radiography of the upper gastrointestinal tract
  • Ultrasonography

Behandlingsmetoder

Behandling måste ordineras av legitimerad veterinär. Specifika doser visas medvetet inte.

Vanliga frågor

What is Lymphoma?

Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.

What are the symptoms of Lymphoma?

Swollen lymph nodes、Loss of appetite、Diarrhoea、Difficulty breathing (dyspnea)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Coughing

How is Lymphoma diagnosed?

Histopathologic Evaluation、Advanced imaging (CT or MRI)、CBC, serum biochemistry profile, and urinalysis、Cerebrospinal fluid (CSF) analysis、FeLV and FIV testing、Fine-needle aspiration (FNA) with cytologic evaluation

How is Lymphoma treated?

Behandling måste ordineras av legitimerad veterinär. Specifika doser visas medvetet inte.

Källor

  1. Internal Medicine 5th · p. 1194
  2. Internal Medicine 5th · p. 1192
  3. Internal Medicine 5th · p. 1194
  4. Internal Medicine 5th · p. 1198
  5. Internal Medicine 5th · p. 1200

Artikeln är allmän information och ersätter inte veterinärråd. Om djuret mår dåligt, kontakta veterinär.

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