Lymphoma
Lymphosarcoma
Juga dikenali sebagai: Malignant lymphoma, Lymphosarcoma
Ringkasnya
Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.
TL;DR. Kanser limfosit lazim di organ pepejal; sering kelenjar bengkak atau masalah pencernaan kronik; bertindak balas baik terhadap kemoterapi.
Sering bengkak tidak sakit kelenjar limfa periferi.
Apakah ia?
Keganasan limfosit dari organ pepejal (kelenjar, hati, limpa, mata), berbeza daripada leukemia limfoid sumsum. Bentuk: multisentrik (anjing kerap), alimentari (kucing kerap), mediastinal, ekstranodal (kulit, mata, buah pinggang, CNS).
Punca dan faktor risiko
Multifaktor. Kucing: kaitan FeLV/FIV. Persekitaran (asap, pestisid) disyaki. Usia pertengahan-tua.
Tanda
- Limfadenopati (kardinal, multisentrik)
- Letargi, sesak/batuk, penurunan berat, anoreksia, muntah/cirit-birit (biasa)
- PU/PD (hiperkalsemia), perubahan mata/kulit, bersin, tanda neuro (kadang-kadang)
Perubahan okular seperti uveitis boleh menyertai.
Diagnosis
Sitologi FNA, biopsi (standard emas), ultrasound (dinding usus), staging (darah, kimia, FeLV/FIV, x-ray/US), imunofenotip (flow/PARR).
Ultrasound menunjukkan penebalan dinding usus tipikal limfoma alimentari.
Rawatan
Sistemik: multiagen CHOP/CEOP (rujukan); COP Protocol alternatif; penyelamatan Lomustine, Cytarabine (CNS). Matlamat: kualiti hidup dan remisi.
Prognosis
Tanpa rawatan: ~4–8 minggu. Anjing CHOP: ~80–90% remisi, ~12–16 bulan. Kucing CHOP: ~65–75%, ~6–9 bulan. Usus small-cell (kucing): kerap >2 tahun.
Pencegahan
Kucing: dalam rumah, perlindungan FeLV. Kurang asap/pestisid. Pemeriksaan senior.
Bila hubungi doktor veterinar
Kecemasan: sesak nafas, buta mendadak, rebah, muntah/cirit berterusan, edema muka, demam/hipotermia.
Sumber
- Small Animal Internal Medicine, 5th Edition, pages 1192, 1194, 1198, 1200.
My highlights & notes
Tanda & simptom
Baka berisiko lebih tinggi
Cara didiagnosis
- Histopathologic EvaluationStandard emas
- Advanced imaging (CT or MRI)
- CBC, serum biochemistry profile, and urinalysis
- Cerebrospinal fluid (CSF) analysis
- FeLV and FIV testing
- Fine-needle aspiration (FNA) with cytologic evaluation
- Flow cytometry
- Immunohistochemistry
- Polymerase chain reaction for antigen receptor rearrangement (PARR)
- Positive contrast-enhanced radiography of the upper gastrointestinal tract
- Ultrasonography
Pendekatan rawatan
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Soalan lazim
What is Lymphoma?
Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.
What are the symptoms of Lymphoma?
Swollen lymph nodes、Loss of appetite、Diarrhoea、Difficulty breathing (dyspnea)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Coughing
How is Lymphoma diagnosed?
Histopathologic Evaluation、Advanced imaging (CT or MRI)、CBC, serum biochemistry profile, and urinalysis、Cerebrospinal fluid (CSF) analysis、FeLV and FIV testing、Fine-needle aspiration (FNA) with cytologic evaluation
How is Lymphoma treated?
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Sumber
- Internal Medicine 5th · p. 1194
- Internal Medicine 5th · p. 1192
- Internal Medicine 5th · p. 1194
- Internal Medicine 5th · p. 1198
- Internal Medicine 5th · p. 1200
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