Lymphoma
Lymphosarcoma
Også kendt som: Malignant lymphoma, Lymphosarcoma
Kort sagt
Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.
TL;DR. Almindelig lymfocytcancer i solide organer; ofte haevede lymfeknuder eller kroniske mave-tarmproblemer; reagerer godt pa kemoterapi.
Ofte smertefri haevelse af perifere lymfeknuder.
Hvad er det?
Malign lymfocytsygdom fra solide organer (lymfeknuder, lever, milt, oje), forskellig fra lymfoid leukami fra knoglemarv. Former: multicentrisk (hund hyppig), alimentær (kat hyppig), mediastinal, extranodal (hud, oje, nyre, CNS).
Arsager og risikofaktorer
Multifaktoriel. Kat: FeLV/FIV-association. Miljo (rog, pesticider) mistænkt. Middelaldrende til aeldre.
Tegn
- Lymfadenopati (kardinal, multicentrisk)
- Letargi, dyspno/hoste, vaegttab, anoreksi, opkast/diarre (hyppige)
- PU/PD (hypercalcaemi), ojen-/hudforandringer, nysen, neurotegn (lejlighedsvis)
Okulaere forandringer som uveitis kan folge med.
Diagnostik
FNA-cytologi, biopsi (guldstandard), ultralyd (tarmvaeg), staging (blodtaelling, kemi, FeLV/FIV, rontgen/UL), immunfenotype (flow/PARR).
Ultralyd viser typisk tarmvaegsfotykkelse ved alimentært lymfom.
Behandling
Systemisk: multiagent CHOP/CEOP (reference); COP Protocol som alternativ; redning Lomustine, Cytarabine (CNS). Mal: livskvalitet og remission.
Prognose
Ubehandlet: ~4–8 uger. Hund CHOP: ~80–90% remission, ~12–16 maneder. Kat CHOP: ~65–75%, ~6–9 maneder. Small-cell intestinal (kat): ofte >2 ar.
Forebyggelse
Kat: inde, FeLV-beskyttelse. Mindre rog/pesticider. Kontroller af seniors.
Nar du skal ringe til dyrlaegen
Akut: andnod, plotlig blindhed, kollaps, vedvarende opkast/diarre, ansigtsodem, feber/hypotermi.
Kilder
- Small Animal Internal Medicine, 5th Edition, pages 1192, 1194, 1198, 1200.
My highlights & notes
Tegn og symptomer
Racer med højere risiko
Hvordan det diagnosticeres
- Histopathologic EvaluationGuldstandard
- Advanced imaging (CT or MRI)
- CBC, serum biochemistry profile, and urinalysis
- Cerebrospinal fluid (CSF) analysis
- FeLV and FIV testing
- Fine-needle aspiration (FNA) with cytologic evaluation
- Flow cytometry
- Immunohistochemistry
- Polymerase chain reaction for antigen receptor rearrangement (PARR)
- Positive contrast-enhanced radiography of the upper gastrointestinal tract
- Ultrasonography
Behandlingsmetoder
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Ofte stillede spørgsmål
What is Lymphoma?
Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.
What are the symptoms of Lymphoma?
Swollen lymph nodes、Loss of appetite、Diarrhoea、Difficulty breathing (dyspnea)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Coughing
How is Lymphoma diagnosed?
Histopathologic Evaluation、Advanced imaging (CT or MRI)、CBC, serum biochemistry profile, and urinalysis、Cerebrospinal fluid (CSF) analysis、FeLV and FIV testing、Fine-needle aspiration (FNA) with cytologic evaluation
How is Lymphoma treated?
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Kilder
- Internal Medicine 5th · p. 1194
- Internal Medicine 5th · p. 1192
- Internal Medicine 5th · p. 1194
- Internal Medicine 5th · p. 1198
- Internal Medicine 5th · p. 1200
Artiklen er generel oplysning og erstatter ikke dyrlægeråd. Hvis dyret er sygt, kontakt en dyrlæge.
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