Lymphoma

Lymphosarcoma

Ayrıca bilinen adıyla: Malignant lymphoma, Lymphosarcoma

CatDogAciliyet: ModerateNe kadar yaygın: Common

Compiled from veterinary literature and clinical references· Updated 2026-07-28·How we create this

Kısaca

Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.

Anatomical diagram of a dog's lymphatic system showing major lymph nodes. — Lymphoma often first presents as painless swelling in the peripheral lymph nodes, which are distributed throughout your pet's body.

TL;DR. Kati organlarda sik lenfosit kanseri; cogu zaman siskin lenf dugumleri veya kronik GI sorunlar; kemoterapiye iyi yanit verir.

Siklikla periferik lenf dugumlerinde agrisiz sisme.

Nedir?

Kati organlardan (lenf dugumu, karaciger, dalak, goz) koken alan lenfosit malignitesi; ilikten kaynaklanan lenfoid losemiden farkli. Formlar: multisentrik (kopek sik), alimenter (kedi sik), mediastinal, ekstranodal (deri, goz, bobrek, MSS).

Nedenler ve risk faktorleri

Cok faktorlu. Kedi: FeLV/FIV baglantisi. Cevre (duman, pestisit) supheli. Orta-yasli-yasli.

Belirtiler

Lenfadenopati (kardinal, multisentrik)
Letarji, dispne/oksuruk, kilo kaybi, anoreksi, kusma/ishal (sik)
PU/PD (hiperkalsemi), goz/deri degisiklikleri, hapşırma, noro bulgular (ara sira)

Close-up of a cat's eye showing cloudiness and redness from anterior uveitis.
Uveit gibi okuler degisiklikler eslik edebilir.

Teshis

FNA sitolojisi, biyopsi (altin standart), ultrason (bagirsak duvari), evreleme (tam kan, biokimya, FeLV/FIV, rontgen/US), immunfenotip (flow/PARR).

Ultrasound monitor showing a thickened intestinal wall in a cat.
Ultrason alimenter lenfomada tipik bagirsak duvari kalinlasmasini gosterir.

Tedavi

Sistemik: cok ajanli CHOP/CEOP (referans); alternatif COP Protocol; kurtarma Lomustine, Cytarabine (MSS). Amac: yasam kalitesi ve remisyon.

Prognoz

Tedavisiz: ~4–8 hafta. Kopek CHOP: ~%80–90 remisyon, ~12–16 ay. Kedi CHOP: ~%65–75, ~6–9 ay. Small-cell intestinal (kedi): siklikla >2 yil.

Onleme

Kedi: ev ici, FeLV korumasi. Daha az duman/pestisit. Yasli kontrolleri.

Ne zaman veterinere basvurulmali

Acil: solunum sikintisi, ani korluk, cokme, surekli kusma/ishal, yuz odemi, ates/hipotermi.

Kaynaklar

Small Animal Internal Medicine, 5th Edition, pages 1192, 1194, 1198, 1200.

My highlights & notes

Belirti ve bulgular

Swollen lymph nodes· Hallmark Loss of appetite· Common Diarrhoea· Common Difficulty breathing (dyspnea)· Common Lethargy· Common Vomiting (throwing up)· Common Weight loss (getting thinner)· Common Coughing· Common Hair loss· Occasional Inflammation inside the eye (anterior uveitis)· Occasional Azotemia (high kidney waste in the blood)· Occasional Blindness (loss of vision)· Occasional Desquamation· Occasional Epiphora· Occasional Skin redness· Occasional Exophthalmos· Occasional Facial deformity· Occasional Nasal discharge· Occasional Neurologic signs· Occasional Polydipsia· Occasional Excessive urination· Occasional Itching and scratching· Occasional Bringing up undigested food· Occasional Enlarged kidney· Occasional Sneezing· Occasional Stertorous breathing· Occasional Squinting (blepharospasm)· Occasional hyphema· Occasional hypopyon· Occasional photophobia· Occasional retinal detachment· Occasional Head and neck edema· Rare

Daha yüksek riskli ırklar

Airedale Terrier Basset Hound Boxer English Cocker Spaniel Golden Retriever Irish Wolfhound Oriental Longhair Rottweiler Shih Tzu Siamese Cat Siberian Husky Yorkshire Terrier Cocker Spaniel Siamese Dog

Nasıl teşhis edilir

Histopathologic EvaluationAltın standart
Advanced imaging (CT or MRI)
CBC, serum biochemistry profile, and urinalysis
Cerebrospinal fluid (CSF) analysis
FeLV and FIV testing
Fine-needle aspiration (FNA) with cytologic evaluation
Flow cytometry
Immunohistochemistry
Polymerase chain reaction for antigen receptor rearrangement (PARR)
Positive contrast-enhanced radiography of the upper gastrointestinal tract
Ultrasonography

Tedavi yaklaşımları

CHOP / CEOP Chemotherapy Protocol· Line 1 COP Chemotherapy Protocol· Line 2 Cytarabine Lomustine

Tedavi, lisanslı veteriner tarafından reçete edilmelidir. Spesifik dozlar kasıtlı gösterilmez.

Sık sorulan sorular

What is Lymphoma?

What are the symptoms of Lymphoma?

Swollen lymph nodes、Loss of appetite、Diarrhoea、Difficulty breathing (dyspnea)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Coughing

How is Lymphoma diagnosed?

Histopathologic Evaluation、Advanced imaging (CT or MRI)、CBC, serum biochemistry profile, and urinalysis、Cerebrospinal fluid (CSF) analysis、FeLV and FIV testing、Fine-needle aspiration (FNA) with cytologic evaluation

How is Lymphoma treated?

Tedavi, lisanslı veteriner tarafından reçete edilmelidir. Spesifik dozlar kasıtlı gösterilmez.

Kaynaklar

Internal Medicine 5th · p. 1194
Internal Medicine 5th · p. 1192
Internal Medicine 5th · p. 1194
Internal Medicine 5th · p. 1198
Internal Medicine 5th · p. 1200

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Orta Doğu

Avrupa

Amerika

Lymphoma

Nedir?

Nedenler ve risk faktorleri

Belirtiler

Teshis

Tedavi

Prognoz

Onleme

Ne zaman veterinere basvurulmali

Kaynaklar

My highlights & notes

Belirti ve bulgular

Daha yüksek riskli ırklar

Nasıl teşhis edilir

Tedavi yaklaşımları

Sık sorulan sorular

Kaynaklar

Evcil hayvanınız için endişeli misiniz?