Lymphoma
Lymphosarcoma
Juga dikenal sebagai: Malignant lymphoma, Lymphosarcoma
Singkatnya
Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.
TL;DR. Kanker limfosit umum di organ padat; sering kelenjar bengkak atau masalah pencernaan kronis; merespons baik terhadap kemoterapi.
Sering pembengkakan tidak nyeri kelenjar getah bening perifer.
Apa itu?
Keganasan limfosit dari organ padat (kelenjar, hati, limpa, mata), berbeda dari leukemia limfoid sumsum. Bentuk: multisentrik (anjing sering), alimenter (kucing sering), mediastinal, ekstranodal (kulit, mata, ginjal, SSP).
Penyebab dan faktor risiko
Multifaktorial. Kucing: kaitan FeLV/FIV. Lingkungan (asap, pestisida) dicurigai. Usia menengah-tua.
Tanda
- Limfadenopati (kardinal, multisentrik)
- Letargi, sesak/batuk, penurunan berat, anoreksia, muntah/diare (umum)
- PU/PD (hiperkalsemia), perubahan mata/kulit, bersin, tanda neuro (kadang)
Perubahan okular seperti uveitis dapat menyertai.
Diagnosis
Sitologi FNA, biopsi (standar emas), USG (dinding usus), staging (darah, kimia, FeLV/FIV, rontgen/USG), imunofenotipe (flow/PARR).
USG menunjukkan penebalan dinding usus tipikal limfoma alimenter.
Pengobatan
Sistemik: multiagen CHOP/CEOP (acuan); COP Protocol alternatif; penyelamatan Lomustine, Cytarabine (SSP). Tujuan: kualitas hidup dan remisi.
Prognosis
Tanpa terapi: ~4–8 minggu. Anjing CHOP: ~80–90% remisi, ~12–16 bulan. Kucing CHOP: ~65–75%, ~6–9 bulan. Usus small-cell (kucing): sering >2 tahun.
Pencegahan
Kucing: indoor, proteksi FeLV. Kurangi asap/pestisida. Pemeriksaan senior.
Kapan menghubungi dokter hewan
Darurat: sesak napas, kebutaan mendadak, kolaps, muntah/diare persisten, edema wajah, demam/hipotermia.
Sumber
- Small Animal Internal Medicine, 5th Edition, pages 1192, 1194, 1198, 1200.
My highlights & notes
Tanda & gejala
Ras berisiko lebih tinggi
Cara didiagnosis
- Histopathologic EvaluationStandar emas
- Advanced imaging (CT or MRI)
- CBC, serum biochemistry profile, and urinalysis
- Cerebrospinal fluid (CSF) analysis
- FeLV and FIV testing
- Fine-needle aspiration (FNA) with cytologic evaluation
- Flow cytometry
- Immunohistochemistry
- Polymerase chain reaction for antigen receptor rearrangement (PARR)
- Positive contrast-enhanced radiography of the upper gastrointestinal tract
- Ultrasonography
Pendekatan pengobatan
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Pertanyaan umum
What is Lymphoma?
Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.
What are the symptoms of Lymphoma?
Swollen lymph nodes、Loss of appetite、Diarrhoea、Difficulty breathing (dyspnea)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Coughing
How is Lymphoma diagnosed?
Histopathologic Evaluation、Advanced imaging (CT or MRI)、CBC, serum biochemistry profile, and urinalysis、Cerebrospinal fluid (CSF) analysis、FeLV and FIV testing、Fine-needle aspiration (FNA) with cytologic evaluation
How is Lymphoma treated?
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Sumber
- Internal Medicine 5th · p. 1194
- Internal Medicine 5th · p. 1192
- Internal Medicine 5th · p. 1194
- Internal Medicine 5th · p. 1198
- Internal Medicine 5th · p. 1200
Artikel ini edukasi umum, bukan pengganti saran dokter hewan. Jika hewan sakit, konsultasikan dokter hewan.
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