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Lymphoma

Lymphosarcoma

Også kjent som: Malignant lymphoma, Lymphosarcoma

VeterinærgodkjentCatDogHaster: ModerateHvor vanlig: Common

Kort fortalt

Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.

Anatomical diagram of a dog's lymphatic system showing major lymph nodes.
Lymphoma often first presents as painless swelling in the peripheral lymph nodes, which are distributed throughout your pet's body.

TL;DR. Vanlig lymfocyttkreft i solide organer; ofte hovne lymfeknuter eller kroniske mage-tarmproblemer; reagerer godt pa cellegift.

Ofte smertefri hevelse av perifere lymfeknuter.

Hva er det?

Malign lymfocyttsykdom fra solide organer (lymfeknuter, lever, milt, oye), ulik lymfoid leukemi fra benmarg. Former: multicentrisk (hund vanlig), alimentær (katt vanlig), mediastinal, extranodal (hud, oye, nyre, CNS).

Arsaker og risikofaktorer

Multifaktoriell. Katt: FeLV/FIV-kobling. Miljo (royk, pesticider) mistenkt. Middelaldrende til eldre.

Tegn

  • Lymfadenopati (kardinal, multicentrisk)
  • Letargi, dyspne/hoste, vekttap, anoreksi, oppkast/diaré (vanlig)
  • PU/PD (hyperkalsemi), oye-/hudforandringer, nysing, nevrotegn (av og til)

Close-up of a cat's eye showing cloudiness and redness from anterior uveitis.
Okulaere forandringer som uveitt kan folge med.

Diagnostikk

FNA-cytologi, biopsi (gullstandard), ultralyd (tarmvegg), staging (blodstatus, kjemi, FeLV/FIV, rontgen/UL), immunfenotype (flow/PARR).

Ultrasound monitor showing a thickened intestinal wall in a cat.
Ultralyd viser typisk tarmveggfortykning ved alimentært lymfom.

Behandling

Systemisk: multiagent CHOP/CEOP (referanse); COP Protocol som alternativ; redning Lomustine, Cytarabine (CNS). Mal: livskvalitet og remisjon.

Prognose

Ubehandlet: ~4–8 uker. Hund CHOP: ~80–90% remisjon, ~12–16 maneder. Katt CHOP: ~65–75%, ~6–9 maneder. Small-cell intestinal (katt): ofte >2 ar.

Forebygging

Katt: innendors, FeLV-beskyttelse. Mindre royk/pesticider. Kontroller av seniors.

Nar du skal ringe veterinaren

Akutt: andnod, plotslig blindhet, kollaps, vedvarende oppkast/diaré, ansiktsodem, feber/hypotermi.

Kilder

  • Small Animal Internal Medicine, 5th Edition, pages 1192, 1194, 1198, 1200.

My highlights & notes

Tegn og symptomer

Raser med høyere risiko

Hvordan det diagnostiseres

  • Histopathologic EvaluationGullstandard
  • Advanced imaging (CT or MRI)
  • CBC, serum biochemistry profile, and urinalysis
  • Cerebrospinal fluid (CSF) analysis
  • FeLV and FIV testing
  • Fine-needle aspiration (FNA) with cytologic evaluation
  • Flow cytometry
  • Immunohistochemistry
  • Polymerase chain reaction for antigen receptor rearrangement (PARR)
  • Positive contrast-enhanced radiography of the upper gastrointestinal tract
  • Ultrasonography

Behandlingsmetoder

Behandling må foreskrives av autorisert veterinær. Spesifikke doser vises bevisst ikke.

Vanlige spørsmål

What is Lymphoma?

Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.

What are the symptoms of Lymphoma?

Swollen lymph nodes、Loss of appetite、Diarrhoea、Difficulty breathing (dyspnea)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Coughing

How is Lymphoma diagnosed?

Histopathologic Evaluation、Advanced imaging (CT or MRI)、CBC, serum biochemistry profile, and urinalysis、Cerebrospinal fluid (CSF) analysis、FeLV and FIV testing、Fine-needle aspiration (FNA) with cytologic evaluation

How is Lymphoma treated?

Behandling må foreskrives av autorisert veterinær. Spesifikke doser vises bevisst ikke.

Kilder

  1. Internal Medicine 5th · p. 1194
  2. Internal Medicine 5th · p. 1192
  3. Internal Medicine 5th · p. 1194
  4. Internal Medicine 5th · p. 1198
  5. Internal Medicine 5th · p. 1200

Artikkelen er generell opplæring og erstatter ikke veterinærråd. Hvis dyret er sykt, kontakt veterinær.

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