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Lymphoma

Lymphosarcoma

Tiež známe ako: Malignant lymphoma, Lymphosarcoma

CatDogNaliehavosť: ModerateAko časté: Common
Compiled from veterinary literature and clinical references· Updated 2026-07-28·How we create this

Stručne

Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.

Anatomical diagram of a dog's lymphatic system showing major lymph nodes.
Lymphoma often first presents as painless swelling in the peripheral lymph nodes, which are distributed throughout your pet's body.

TL;DR. Caste nadorove ochorenie lymfocytov v pevnych organoch; casto zdurene uzliny alebo chronicke GI potaze; dobre reaguje na chemoterapiu.

Casto nebolestive zdurenie perifernych lymfatickych uzlin.

Co to je?

Zhubne ochorenie lymfocytov z pevnych organov (uzliny, pecen, slezina, oko), odlisne od lymfoidnej leukemie z kostnej drene. Formy: multicentricka (pes casto), alimentarna (macka casto), mediastinalna, extranodalna (koza, oko, oblicka, CNS).

Priciny a rizikove faktory

Multifaktorialne. Macka: suvislost FeLV/FIV. Prostredie (dym, pesticidy) podozrive. Stredny az starsi vek.

Znamky

  • Lymfadenopatia (kardinalna, multicentricka)
  • Letargia, dyspnoe/kasel, chudnutie, anorexia, zvracanie/hnacka (caste)
  • PU/PD (hyperkalcemia), ocne/kozne zmeny, kychanie, neuro znamky (obcasne)

Close-up of a cat's eye showing cloudiness and redness from anterior uveitis.
Ocne zmeny ako uveitida mozu sprevadzat.

Ako diagnostikuju veterinari

Cytologia FNA, biopsia (zlaty standard), ultrazvuk (stena creva), staging (KO, biochemia, FeLV/FIV, RTG/UZ), imunofenotyp (flow/PARR).

Ultrasound monitor showing a thickened intestinal wall in a cat.
Ultrazvuk ukazuje typicke zhrubnutie steny creva pri alimentarnej lymfome.

Liecba

Systemova: multiagent CHOP/CEOP (referencia); COP Protocol ako alternativa; zachrana Lomustine, Cytarabine (CNS). Ciel: kvalita zivota a remisia.

Prognoza

Bez liecby: ~4–8 tyzdnov. Pes CHOP: ~80–90% remisii, ~12–16 mesiacov. Macka CHOP: ~65–75%, ~6–9 mesiacov. Small-cell crevny (macka): casto >2 roky.

Prevencia

Macka: interier, ochrana FeLV. Menej dymu/pesticidov. Kontroly seniorov.

Kedy volat veterinara

Naliehave: dychacia tiesen, nahla slepota, kolaps, pretrvavajuce zvracanie/hnacka, edem tvare, horucka/hypotermia.

Zdroje

  • Small Animal Internal Medicine, 5th Edition, pages 1192, 1194, 1198, 1200.

My highlights & notes

Príznaky a prejavy

Swollen lymph nodes· HallmarkLoss of appetite· CommonDiarrhoea· CommonDifficulty breathing (dyspnea)· CommonLethargy· CommonVomiting (throwing up)· CommonWeight loss (getting thinner)· CommonCoughing· CommonHair loss· OccasionalInflammation inside the eye (anterior uveitis)· OccasionalAzotemia (high kidney waste in the blood)· OccasionalBlindness (loss of vision)· OccasionalDesquamation· OccasionalEpiphora· OccasionalSkin redness· OccasionalExophthalmos· OccasionalFacial deformity· OccasionalNasal discharge· OccasionalNeurologic signs· OccasionalPolydipsia· OccasionalExcessive urination· OccasionalItching and scratching· OccasionalBringing up undigested food· OccasionalEnlarged kidney· OccasionalSneezing· OccasionalStertorous breathing· OccasionalSquinting (blepharospasm)· Occasionalhyphema· Occasionalhypopyon· Occasionalphotophobia· Occasionalretinal detachment· OccasionalHead and neck edema· Rare

Plemená s vyšším rizikom

Airedale TerrierBasset HoundBoxerEnglish Cocker SpanielGolden RetrieverIrish WolfhoundOriental LonghairRottweilerShih TzuSiamese CatSiberian HuskyYorkshire TerrierCocker SpanielSiamese Dog

Ako sa diagnostikuje

  • Histopathologic EvaluationZlatý štandard
  • Advanced imaging (CT or MRI)
  • CBC, serum biochemistry profile, and urinalysis
  • Cerebrospinal fluid (CSF) analysis
  • FeLV and FIV testing
  • Fine-needle aspiration (FNA) with cytologic evaluation
  • Flow cytometry
  • Immunohistochemistry
  • Polymerase chain reaction for antigen receptor rearrangement (PARR)
  • Positive contrast-enhanced radiography of the upper gastrointestinal tract
  • Ultrasonography

Prístupy k liečbe

CHOP / CEOP Chemotherapy Protocol· Line 1COP Chemotherapy Protocol· Line 2CytarabineLomustine

Liečbu musí predpísať licencovaný veterinár. Konkrétne dávky zámerne neuvedujeme.

Časté otázky

What is Lymphoma?

Lymphoma is a common and treatable cancer of the immune system in dogs and cats. Originating in solid organs like the lymph nodes, spleen, or intestines, it presents in several distinct forms. Learn how to recognize the signs, what diagnostic tests your vet will perform, and how modern chemotherapy protocols can extend your pet's life while preserving their daily quality of life.

What are the symptoms of Lymphoma?

Swollen lymph nodes、Loss of appetite、Diarrhoea、Difficulty breathing (dyspnea)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Coughing

How is Lymphoma diagnosed?

Histopathologic Evaluation、Advanced imaging (CT or MRI)、CBC, serum biochemistry profile, and urinalysis、Cerebrospinal fluid (CSF) analysis、FeLV and FIV testing、Fine-needle aspiration (FNA) with cytologic evaluation

How is Lymphoma treated?

Liečbu musí predpísať licencovaný veterinár. Konkrétne dávky zámerne neuvedujeme.

Zdroje

  1. Internal Medicine 5th · p. 1194
  2. Internal Medicine 5th · p. 1192
  3. Internal Medicine 5th · p. 1194
  4. Internal Medicine 5th · p. 1198
  5. Internal Medicine 5th · p. 1200

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