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Ethylene Glycol Toxicity

Även känd som: Ethylene glycol poisoning, Ethylene glycol intoxication, Antifreeze poisoning

CatDogBrådska: EmergencyHur vanligt: Common

Kort sagt

Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.

A cat sniffing a green puddle of antifreeze on a garage floor.
Antifreeze spills are highly attractive to pets due to their sweet taste.

TL;DR. Kylarvätska ger permanent njursvikt utan antidot inom timmar; minuter räknas.

Söta pölar lockar djur.

Vad är det?

Sweet antifreeze/de-icer. Liver metabolites cause severe metabolic acidosis and renal tubular necrosis with calcium oxalate crystals. Minutes matter.

Orsaker och riskfaktorer

Automotive antifreeze, some washer fluids. Outdoor access to garages. Cats: ~1 teaspoon can kill; dogs: a few tablespoons.

Tecken

  • Phase 1 (0.5-12 h): ataxia, vomiting, polyuria/polydipsia ("drunk")
  • Phase 2 (12-24 h): seeming improvement but tachycardia/tachypnea
  • Phase 3 (12-72 h): severe depression, anuria, seizures, uremic breath

A dog looking weak and unsteady on a living room rug.
Tidig fas som berusning: ostadighet.

Diagnostik

Rapid ethylene glycol blood screen (early only), urinalysis for oxalate crystals, chemistry/blood gas for azotemia and high anion-gap acidosis.

A veterinary technician preparing a rapid blood screening test kit.
Snabb blodscreening före full metabolism.

Behandling

Antidotes: preferred Fomepizole; if unavailable Ethanol. Never combine. Aggressive IV fluids; hemodialysis if available.

Prognos

Dogs: good if antidote within ~8 h. Cats: good only within ~3 h; delay beyond ~4 h nearly always fatal without hemodialysis.

Prevention

Seal antifreeze high and dry; clean spills immediately; prefer propylene-glycol coolants; leash walks; keep cats indoors.

När ringa

Any suspected antifreeze exposure is Level-5 emergency. Do not wait for "drunk" signs; go to ER now.

Källor

  • Small Animal Critical Care Medicine, 2nd Edition, page 437.
  • Plumb's Veterinary Drug Handbook, pages 1411, 1594, 1596.

My highlights & notes

Tecken & symptom

Hur det diagnostiseras

  • Ethylene glycol screening test

Behandlingsmetoder

Behandling måste ordineras av legitimerad veterinär. Specifika doser visas medvetet inte.

Vanliga frågor

What is Ethylene Glycol Toxicity?

Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.

What are the symptoms of Ethylene Glycol Toxicity?

Acute kidney injury、Calcium oxalate crystal formation、Metabolic acidosis、Renal tubular necrosis、Azotemia (high kidney waste in the blood)

How is Ethylene Glycol Toxicity diagnosed?

Ethylene glycol screening test

How is Ethylene Glycol Toxicity treated?

Behandling måste ordineras av legitimerad veterinär. Specifika doser visas medvetet inte.

Källor

  1. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 437
  2. Plumb · p. 1594
  3. Plumb · p. 1411
  4. Plumb · p. 1596

Artikeln är allmän information och ersätter inte veterinärråd. Om djuret mår dåligt, kontakta veterinär.

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