Ethylene Glycol Toxicity
Også kendt som: Ethylene glycol poisoning, Ethylene glycol intoxication, Antifreeze poisoning
Kort sagt
Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.
TL;DR. Kølervæske giver permanent nyresvigt uden antidot inden for timer; minutter tæller.
Søde pytter tiltrækker dyr.
Hvad er det?
Sweet antifreeze/de-icer. Liver metabolites cause severe metabolic acidosis and renal tubular necrosis with calcium oxalate crystals. Minutes matter.
Årsager og risikofaktorer
Automotive antifreeze, some washer fluids. Outdoor access to garages. Cats: ~1 teaspoon can kill; dogs: a few tablespoons.
Tegn
- Phase 1 (0.5-12 h): ataxia, vomiting, polyuria/polydipsia ("drunk")
- Phase 2 (12-24 h): seeming improvement but tachycardia/tachypnea
- Phase 3 (12-72 h): severe depression, anuria, seizures, uremic breath
Tidlig fase som beruselse: usikkerhed.
Diagnostik
Rapid ethylene glycol blood screen (early only), urinalysis for oxalate crystals, chemistry/blood gas for azotemia and high anion-gap acidosis.
Hurtig blodscreenting før fuld metabolisering.
Behandling
Antidotes: preferred Fomepizole; if unavailable Ethanol. Never combine. Aggressive IV fluids; hemodialysis if available.
Prognose
Dogs: good if antidote within ~8 h. Cats: good only within ~3 h; delay beyond ~4 h nearly always fatal without hemodialysis.
Forebyggelse
Seal antifreeze high and dry; clean spills immediately; prefer propylene-glycol coolants; leash walks; keep cats indoors.
Hvornår ringe
Any suspected antifreeze exposure is Level-5 emergency. Do not wait for "drunk" signs; go to ER now.
Kilder
- Small Animal Critical Care Medicine, 2nd Edition, page 437.
- Plumb's Veterinary Drug Handbook, pages 1411, 1594, 1596.
My highlights & notes
Tegn og symptomer
Hvordan det diagnosticeres
- Ethylene glycol screening test
Behandlingsmetoder
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Ofte stillede spørgsmål
What is Ethylene Glycol Toxicity?
Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.
What are the symptoms of Ethylene Glycol Toxicity?
Acute kidney injury、Calcium oxalate crystal formation、Metabolic acidosis、Renal tubular necrosis、Azotemia (high kidney waste in the blood)
How is Ethylene Glycol Toxicity diagnosed?
Ethylene glycol screening test
How is Ethylene Glycol Toxicity treated?
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Kilder
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 437
- Plumb · p. 1594
- Plumb · p. 1411
- Plumb · p. 1596
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