Ethylene Glycol Toxicity
Juga dikenali sebagai: Ethylene glycol poisoning, Ethylene glycol intoxication, Antifreeze poisoning
Ringkasnya
Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.
TL;DR. Cecair antibeku menyebabkan kegagalan buah pinggang kekal tanpa antidot dalam jam; minit penting.
Genangan manis menarik haiwan.
Apakah itu?
Sweet antifreeze/de-icer. Liver metabolites cause severe metabolic acidosis and renal tubular necrosis with calcium oxalate crystals. Minutes matter.
Punca dan faktor risiko
Automotive antifreeze, some washer fluids. Outdoor access to garages. Cats: ~1 teaspoon can kill; dogs: a few tablespoons.
Tanda
- Phase 1 (0.5-12 h): ataxia, vomiting, polyuria/polydipsia ("drunk")
- Phase 2 (12-24 h): seeming improvement but tachycardia/tachypnea
- Phase 3 (12-72 h): severe depression, anuria, seizures, uremic breath
Fasa awal seperti mabuk: goyah.
Diagnostik
Rapid ethylene glycol blood screen (early only), urinalysis for oxalate crystals, chemistry/blood gas for azotemia and high anion-gap acidosis.
Saringan darah pantas sebelum metabolisme penuh.
Rawatan
Antidotes: preferred Fomepizole; if unavailable Ethanol. Never combine. Aggressive IV fluids; hemodialysis if available.
Prognosis
Dogs: good if antidote within ~8 h. Cats: good only within ~3 h; delay beyond ~4 h nearly always fatal without hemodialysis.
Pencegahan
Seal antifreeze high and dry; clean spills immediately; prefer propylene-glycol coolants; leash walks; keep cats indoors.
Bila hubungi
Any suspected antifreeze exposure is Level-5 emergency. Do not wait for "drunk" signs; go to ER now.
Sumber
- Small Animal Critical Care Medicine, 2nd Edition, page 437.
- Plumb's Veterinary Drug Handbook, pages 1411, 1594, 1596.
My highlights & notes
Tanda & simptom
Cara didiagnosis
- Ethylene glycol screening test
Pendekatan rawatan
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Soalan lazim
What is Ethylene Glycol Toxicity?
Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.
What are the symptoms of Ethylene Glycol Toxicity?
Acute kidney injury、Calcium oxalate crystal formation、Metabolic acidosis、Renal tubular necrosis、Azotemia (high kidney waste in the blood)
How is Ethylene Glycol Toxicity diagnosed?
Ethylene glycol screening test
How is Ethylene Glycol Toxicity treated?
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Sumber
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 437
- Plumb · p. 1594
- Plumb · p. 1411
- Plumb · p. 1596
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