Ethylene Glycol Toxicity
Juga dikenal sebagai: Ethylene glycol poisoning, Ethylene glycol intoxication, Antifreeze poisoning
Singkatnya
Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.
TL;DR. Keracunan etilen glikol (antibeku) darurat; gagal ginjal permanen tanpa antidot dalam hitungan jam.
Tumpahan antibeku manis menarik hewan.
Apa itu?
Antibeku/de-icer manis. Metabolit hati menyebabkan asidosis metabolik berat dan nekrosis tubulus ginjal dengan kristal kalsium oksalat. Menit penting.
Penyebab dan faktor risiko
Antibeku otomotif, beberapa cairan pencuci kaca. Akses garasi/jalan. Kucing: ~1 sendok teh bisa mematikan; anjing: beberapa sendok makan.
Tanda
- Fase 1 (0.5–12 jam): ataksia, muntah, poliuria/polidipsia ("mabuk")
- Fase 2 (12–24 jam): tampak membaik tapi takikardia/takipnea
- Fase 3 (12–72 jam): depresi berat, anuria, kejang, napas uremik
- Asidosis metabolik, AKI, nekrosis tubulus, kristal oksalat (umum)
Fase awal seperti mabuk: goyah.
Diagnosis
Skrining EG darah (hanya dini), urinalisis kristal picket-fence, kimia/gas darah: azotemia dan asidosis anion gap tinggi.
"Once the patient has been appropriately decontaminated, the focus of treatment should be based on symptomatic and supportive care."
Skrining darah cepat sebelum metabolisme penuh.
Pengobatan
Antidot: Fomepizole; jika tidak ada Ethanol. Jangan gabung keduanya. Cairan IV agresif; hemodialisis jika tersedia.
Prognosis
Anjing: baik jika antidot ≤~8 jam. Kucing: baik hanya ≤~3 jam; >~4 jam hampir fatal tanpa hemodialisis. AKI anurik: buruk.
Pencegahan
Simpan antibeku aman; bersihkan tumpahan; pilih pendingin propilen glikol; tali; kucing indoor.
Kapan ke dokter hewan
Setiap dugaan paparan antibeku adalah darurat level 5. Jangan tunggu tanda "mabuk".
Sumber
- Small Animal Critical Care Medicine, 2nd Edition, page 437.
- Plumb's Veterinary Drug Handbook, pages 1411, 1594, 1596.
My highlights & notes
Tanda & gejala
Cara didiagnosis
- Ethylene glycol screening test
Pendekatan pengobatan
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Pertanyaan umum
What is Ethylene Glycol Toxicity?
Ethylene glycol toxicity, commonly known as antifreeze poisoning, is a rapid and deadly emergency for dogs and cats. Ingesting even a tiny amount can cause irreversible kidney failure within hours. Learn the critical signs, diagnostic steps, and why immediate veterinary treatment is the only way to save your pet's life.
What are the symptoms of Ethylene Glycol Toxicity?
Acute kidney injury、Calcium oxalate crystal formation、Metabolic acidosis、Renal tubular necrosis、Azotemia (high kidney waste in the blood)
How is Ethylene Glycol Toxicity diagnosed?
Ethylene glycol screening test
How is Ethylene Glycol Toxicity treated?
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Sumber
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 437
- Plumb · p. 1594
- Plumb · p. 1411
- Plumb · p. 1596
Artikel ini edukasi umum, bukan pengganti saran dokter hewan. Jika hewan sakit, konsultasikan dokter hewan.
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