Cutaneous Lymphoma
Cutaneous lymphoma
Også kendt som: Epitheliotropic Lymphoma, Nonepitheliotropic Lymphoma, Mycosis Fungoides, Cutaneous Lymphosarcoma
Kort sagt
Cutaneous lymphoma is an uncommon but serious skin cancer in dogs and cats where abnormal white blood cells accumulate in the skin, causing persistent redness, scaling, hair loss, or lumps that can easily be mistaken for chronic allergies.

TL;DR. Usædvanlig men alvorlig hudkræft: unormale lymfocytter i huden med rødme, skæl, hårtab eller knuder; ofte forvekslet med allergi.
Udbredt hårtab, rødme og skæl kan ligne allergi.
Hvad er det?
Maligne lymfocytter i huden. Epiteliotróp (ofte T-celler, epidermis/mund) vs ikke-epiteliotróp (B/T, dermale/subkutane knuder).
"Nonepitheliotropic lymphoma is a malignant neoplasm that may arise from B or T lymphocytes. It is uncommon in dogs and cats, with highest incidence in older animals. Usually, nonepitheliotropic lymphoma appears as multiple, firm,"
Årsager og risikofaktorer
Årsag uklar. Alder øger risiko. Hunderacer: Boxers, Scottish Terriers, Golden Retrievers, Rottweilers.
Tegn
- Almindelige: kløe, skæl, plaques/knuder, erytem, alopeci
- Lejlighedsvis: trædepudehyperkeratose, orale sår, mukokutan depigmentering, lymfadenomegali

Mukokutan depigmentering og sår mulige.
Diagnostik
FNA begrænset; biopsi/histopatologi guldstandard. Staging: blod, ultralyd, thoraxrøntgen, lymfeknude-FNA.
"Distinguishing these requires a biopsy sample to assess the tissue distribution of lymphocytes in relation to the epidermis, and this cannot be done with cytological samples."
Behandling
Systemisk: COP Chemotherapy Protocol. Støtte: antibiotika/antimykotika, medicinske bade, analgesi.
Prognose
Langsomt progressiv, helbredelse sjælden. Epiteliotróp ofte langsommere; ikke-epiteliotróp ofte mere aggressiv/systemisk tidligere.
Forebyggelse
Ingen sikker forebyggelse. Tidlig biopsi ved refraktær dermatose.
Hvornår ringe til dyrlæge
Akut: kollaps; vedvarende opkast/diarré; spændt bug; åndenød.
For bestemte racer
Boxer, Scottish Terrier, Golden Retriever, Rottweiler: udred tidligt kroniske hudforandringer og knuder, ikke kun som allergi.
Kilder
- Veterinary Internal Medicine, 5th Edition, page 1195.
- Small Animal Dermatology: A Color Atlas and Therapeutic Guide, page 472.
- Cowell and Tyler's Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition, page 104.
My highlights & notes
Tegn og symptomer
Racer med højere risiko
Hvordan det diagnosticeres
- Biopsy and histopathologyGuldstandard
- Cytology (Fine needle aspirate)
- Screening for internal organ and lymph node involvement
Behandlingsmetoder
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Ofte stillede spørgsmål
What is Cutaneous Lymphoma?
Cutaneous lymphoma is an uncommon but serious skin cancer in dogs and cats where abnormal white blood cells accumulate in the skin, causing persistent redness, scaling, hair loss, or lumps that can easily be mistaken for chronic allergies.
What are the symptoms of Cutaneous Lymphoma?
Hair loss、Desquamation and scaling、Skin redness、Plaques or nodules、Itching and scratching、Doughnut-shaped dermoepidermal mass、Footpad hyperkeratosis、Mucocutaneous depigmentation and ulceration
How is Cutaneous Lymphoma diagnosed?
Biopsy and histopathology、Cytology (Fine needle aspirate)、Screening for internal organ and lymph node involvement
How is Cutaneous Lymphoma treated?
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Kilder
- Internal Medicine 5th · p. 1195
- Internal Medicine 5th · p. 1195
- 皮膚病 教科書點子書 Small-Animal-Dermatology-A-Color-Atlas-and-Therapeutic-Guide · p. 472
- Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 104
- Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 104
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