Cutaneous Lymphoma
Cutaneous lymphoma
Juga dikenal sebagai: Epitheliotropic Lymphoma, Nonepitheliotropic Lymphoma, Mycosis Fungoides, Cutaneous Lymphosarcoma
Singkatnya
Cutaneous lymphoma is an uncommon but serious skin cancer in dogs and cats where abnormal white blood cells accumulate in the skin, causing persistent redness, scaling, hair loss, or lumps that can easily be mistaken for chronic allergies.
TL;DR. Kanker kulit jarang tapi serius: limfosit abnormal di kulit dengan kemerahan, sisik, kerontokan bulu atau nodul; sering disalahartikan sebagai alergi.
Kerontokan bulu, kemerahan, dan sisik luas dapat menyerupai alergi.
Apa itu?
Limfosit ganas di kulit. Epiteliotrópik (sering T, epidermis/mulut) vs non-epiteliotrópik (B/T, nodul dermal/subkutan).
"Nonepitheliotropic lymphoma is a malignant neoplasm that may arise from B or T lymphocytes. It is uncommon in dogs and cats, with highest incidence in older animals. Usually, nonepitheliotropic lymphoma appears as multiple, firm,"
Penyebab dan faktor risiko
Penyebab tidak jelas. Usia meningkatkan risiko. Ras anjing: Boxers, Scottish Terriers, Golden Retrievers, Rottweilers.
Tanda
- Umum: gatal, sisik, plak/nodul, eritema, alopecia
- Kadang: hiperkeratosis bantalan kaki, ulkus oral, depigmentasi mukokutaneus, limfadenomegali
Depigmentasi dan ulkus mukokutaneus mungkin.
Diagnosis
FNA terbatas; biopsi/histopatologi standar emas. Staging: darah, USG, radiografi toraks, FNA kelenjar getah bening.
"Distinguishing these requires a biopsy sample to assess the tissue distribution of lymphocytes in relation to the epidermis, and this cannot be done with cytological samples."
Pengobatan
Sistemik: COP Chemotherapy Protocol. Dukungan: antibiotik/antijamur, mandi obat, analgesia.
Prognosis
Progresif lambat, kesembuhan jarang. Epiteliotrópik sering lebih lambat; non-epiteliotrópik sering lebih agresif/sistemik lebih awal.
Pencegahan
Tidak ada pencegahan terbukti. Biopsi dini pada dermatosis refrakter.
Kapan memanggil dokter hewan
Darurat: rebah; muntah/diare persisten; abdomen tegang; sesak napas.
Untuk ras tertentu
Boxer, Scottish Terrier, Golden Retriever, Rottweiler: evaluasi dini perubahan kulit kronis dan nodul, jangan hanya dianggap alergi.
Sumber
- Veterinary Internal Medicine, 5th Edition, page 1195.
- Small Animal Dermatology: A Color Atlas and Therapeutic Guide, page 472.
- Cowell and Tyler's Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition, page 104.
My highlights & notes
Tanda & gejala
Ras berisiko lebih tinggi
Cara didiagnosis
- Biopsy and histopathologyStandar emas
- Cytology (Fine needle aspirate)
- Screening for internal organ and lymph node involvement
Pendekatan pengobatan
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Pertanyaan umum
What is Cutaneous Lymphoma?
Cutaneous lymphoma is an uncommon but serious skin cancer in dogs and cats where abnormal white blood cells accumulate in the skin, causing persistent redness, scaling, hair loss, or lumps that can easily be mistaken for chronic allergies.
What are the symptoms of Cutaneous Lymphoma?
Hair loss、Desquamation and scaling、Skin redness、Plaques or nodules、Itching and scratching、Doughnut-shaped dermoepidermal mass、Footpad hyperkeratosis、Mucocutaneous depigmentation and ulceration
How is Cutaneous Lymphoma diagnosed?
Biopsy and histopathology、Cytology (Fine needle aspirate)、Screening for internal organ and lymph node involvement
How is Cutaneous Lymphoma treated?
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Sumber
- Internal Medicine 5th · p. 1195
- Internal Medicine 5th · p. 1195
- 皮膚病 教科書點子書 Small-Animal-Dermatology-A-Color-Atlas-and-Therapeutic-Guide · p. 472
- Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 104
- Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 104
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