Cutaneous Lymphoma
Cutaneous lymphoma
Juga dikenali sebagai: Epitheliotropic Lymphoma, Nonepitheliotropic Lymphoma, Mycosis Fungoides, Cutaneous Lymphosarcoma
Ringkasnya
Cutaneous lymphoma is an uncommon but serious skin cancer in dogs and cats where abnormal white blood cells accumulate in the skin, causing persistent redness, scaling, hair loss, or lumps that can easily be mistaken for chronic allergies.
TL;DR. Kanser kulit jarang tetapi serius: limfosit abnormal pada kulit dengan kemerahan, pengelupasan, keguguran bulu atau nodul; sering disalah anggap alergi.
Keguguran bulu, kemerahan dan pengelupasan meluas boleh menyerupai alergi.
Apakah ia?
Limfosit malignan dalam kulit. Epiteliotrópik (sering T, epidermis/mulut) vs bukan epiteliotrópik (B/T, nodul dermal/subkutaneus).
"Nonepitheliotropic lymphoma is a malignant neoplasm that may arise from B or T lymphocytes. It is uncommon in dogs and cats, with highest incidence in older animals. Usually, nonepitheliotropic lymphoma appears as multiple, firm,"
Punca dan faktor risiko
Punca tidak jelas. Umur meningkatkan risiko. Baka anjing: Boxers, Scottish Terriers, Golden Retrievers, Rottweilers.
Tanda
- Biasa: gatal, pengelupasan, plak/nodul, eritema, alopecia
- Kadang-kadang: hiperkeratosis pad kaki, ulser oral, depigmentasi mukokutaneus, limfadenomegali
Depigmentasi dan ulser mukokutaneus mungkin.
Diagnosis
FNA terhad; biopsi/histopatologi piawai emas. Staging: darah, ultrasound, radiograf toraks, FNA nodus limfa.
"Distinguishing these requires a biopsy sample to assess the tissue distribution of lymphocytes in relation to the epidermis, and this cannot be done with cytological samples."
Rawatan
Sistemik: COP Chemotherapy Protocol. Sokongan: antibiotik/antifungal, mandian perubatan, analgesia.
Prognosis
Progresif perlahan, penyembuhan jarang. Epiteliotrópik sering lebih perlahan; bukan epiteliotrópik sering lebih agresif/sistemik lebih awal.
Pencegahan
Tiada pencegahan terbukti. Biopsi awal pada dermatosis refraktori.
Bila hubungi doktor haiwan
Kecemasan: rebah; muntah/cirit-birit berterusan; abdomen tegang; sesak nafas.
Untuk baka tertentu
Boxer, Scottish Terrier, Golden Retriever, Rottweiler: nilai awal perubahan kulit kronik dan nodul, bukan hanya sebagai alergi.
Sumber
- Veterinary Internal Medicine, 5th Edition, page 1195.
- Small Animal Dermatology: A Color Atlas and Therapeutic Guide, page 472.
- Cowell and Tyler's Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition, page 104.
My highlights & notes
Tanda & simptom
Baka berisiko lebih tinggi
Cara didiagnosis
- Biopsy and histopathologyStandard emas
- Cytology (Fine needle aspirate)
- Screening for internal organ and lymph node involvement
Pendekatan rawatan
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Soalan lazim
What is Cutaneous Lymphoma?
Cutaneous lymphoma is an uncommon but serious skin cancer in dogs and cats where abnormal white blood cells accumulate in the skin, causing persistent redness, scaling, hair loss, or lumps that can easily be mistaken for chronic allergies.
What are the symptoms of Cutaneous Lymphoma?
Hair loss、Desquamation and scaling、Skin redness、Plaques or nodules、Itching and scratching、Doughnut-shaped dermoepidermal mass、Footpad hyperkeratosis、Mucocutaneous depigmentation and ulceration
How is Cutaneous Lymphoma diagnosed?
Biopsy and histopathology、Cytology (Fine needle aspirate)、Screening for internal organ and lymph node involvement
How is Cutaneous Lymphoma treated?
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Sumber
- Internal Medicine 5th · p. 1195
- Internal Medicine 5th · p. 1195
- 皮膚病 教科書點子書 Small-Animal-Dermatology-A-Color-Atlas-and-Therapeutic-Guide · p. 472
- Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 104
- Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 104
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