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Aortic Thromboembolism

Systemic arterial thromboembolism

Også kendt som: FATE, Feline Aortic Thromboembolism, Saddle Thrombus, Saddle Embolus, Systemic Arterial Thromboembolism

CatDogHastighed: Emergency

Kort sagt

Aortic thromboembolism, or saddle thrombus, is a sudden, life-threatening emergency in dogs and cats where a blood clot blocks blood flow to the hind limbs. This guide explains the causes, critical warning signs, diagnostic process, and intensive treatment options for this severe cardiovascular condition.

Anatomy diagram of a saddle thrombus blocking blood flow to a pet's hind legs.
A saddle thrombus lodges at the aortic trifurcation, completely blocking blood flow to the hind limbs.

TL;DR. Sadeltrombe: pludselig nød der blokerer flow til bagbenene; ekstrem smerte og lammelse.

Tromben sidder ved aortatrifurkationen.

Hvad er det?

Saddle thrombus: cardiac embolus lodges at the aortic trifurcation, cutting hind-limb flow. Ischemia leads to rhabdomyolysis, nerve injury, paresis/paralysis, and extreme pain.

Årsager og risikofaktorer

Cat: usually HCM with enlarged left atrium. Dog: hypercoagulable states (Cushing, protein-losing nephropathy, IMHA, neoplasia, sepsis, pancreatitis, etc.).

Tegn at holde øje med

  • Severe pain, hind paresis/paralysis, absent femoral pulses (cardinal)
  • Cold limbs, pale/cyanotic pads, tachypnea, hypothermia (common)
  • Muscle contracture, murmur/arrhythmia (occasional)

Close-up of pale and bluish cat footpads indicating a lack of blood flow.
Blege eller blålige trædepuder og kolde poter er klassiske.

Hvordan dyrlæger diagnosticerer

Clinical five Ps (pain, paresis, pulselessness, pallor, poikilothermia). Echocardiography, abdominal ultrasound/Doppler, thoracic radiographs before diuretics, CK/AST, TEG if available.

Echocardiogram showing a blood clot in an enlarged left atrium.
Echo viser forkammerforstørrelse og ofte trombe eller røg.

Behandlingsmuligheder

Opioid analgesia. Anticoagulation: heparin, LMWH; long-term clopidogrel, sometimes aspirin. Oxygen; cautious fluids. Monitor reperfusion injury (hyperkalemia).

Prognose

Poor: high acute mortality/euthanasia; recurrences common.

Forebyggelse

Early cardiac screening; clopidogrel if marked LA enlargement. Treat underlying disease in dogs.

Hvornår ringe til dyrlægen

Category-5 emergency: sudden hind-limb paralysis, crying in pain, cold pale paws, severe dyspnea.

Kilder

  • Small Animal Critical Care Medicine, 2nd Edition, p. 253
  • Textbook of Veterinary Internal Medicine, 5th Edition, pp. 235, 236, 244

My highlights & notes

Tegn og symptomer

Racer med højere risiko

Hvordan det diagnosticeres

  • Abdominal Ultrasonography
  • Angiography
  • Doppler studies
  • Echocardiography
  • Measurement of muscle enzymes
  • Thoracic radiography
  • Thromboelastography

Behandlingsmetoder

Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.

Ofte stillede spørgsmål

What is Aortic Thromboembolism?

Aortic thromboembolism, or saddle thrombus, is a sudden, life-threatening emergency in dogs and cats where a blood clot blocks blood flow to the hind limbs. This guide explains the causes, critical warning signs, diagnostic process, and intensive treatment options for this severe cardiovascular condition.

What are the symptoms of Aortic Thromboembolism?

Absent arterial pulse、Acute limb paresis、Pain、Posterior paresis、Azotemia (high kidney waste in the blood)、Cool distal limbs、Cyanotic nailbeds、Difficulty breathing (dyspnea)

How is Aortic Thromboembolism diagnosed?

Abdominal Ultrasonography、Angiography、Doppler studies、Echocardiography、Measurement of muscle enzymes、Thoracic radiography

How is Aortic Thromboembolism treated?

Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.

Kilder

  1. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 253
  2. Internal Medicine 5th · p. 236
  3. Internal Medicine 5th · p. 244
  4. Internal Medicine 5th · p. 235
  5. Internal Medicine 5th · p. 236

Artiklen er generel oplysning og erstatter ikke dyrlægeråd. Hvis dyret er sygt, kontakt en dyrlæge.

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