Aortic Thromboembolism
Systemic arterial thromboembolism
Ook bekend als: FATE, Feline Aortic Thromboembolism, Saddle Thrombus, Saddle Embolus, Systemic Arterial Thromboembolism
Kort samengevat
Aortic thromboembolism, or saddle thrombus, is a sudden, life-threatening emergency in dogs and cats where a blood clot blocks blood flow to the hind limbs. This guide explains the causes, critical warning signs, diagnostic process, and intensive treatment options for this severe cardiovascular condition.
TL;DR. Zadelthrombus: plotselinge nood die de doorbloeding naar de achterpoten blokkeert; extreme pijn en verlamming.
De zadelthrombus zit op de aortatrifurcatie.
Wat is het?
Saddle thrombus: cardiac embolus lodges at the aortic trifurcation, cutting hind-limb flow. Ischemia leads to rhabdomyolysis, nerve injury, paresis/paralysis, and extreme pain.
Oorzaken en risicofactoren
Cat: usually HCM with enlarged left atrium. Dog: hypercoagulable states (Cushing, protein-losing nephropathy, IMHA, neoplasia, sepsis, pancreatitis, etc.).
Signalen
- Severe pain, hind paresis/paralysis, absent femoral pulses (cardinal)
- Cold limbs, pale/cyanotic pads, tachypnea, hypothermia (common)
- Muscle contracture, murmur/arrhythmia (occasional)
Bleke of blauwachtige voetzolen en koude poten zijn klassiek.
Diagnostiek
Clinical five Ps (pain, paresis, pulselessness, pallor, poikilothermia). Echocardiography, abdominal ultrasound/Doppler, thoracic radiographs before diuretics, CK/AST, TEG if available.
Echo toont atriumvergroting en vaak trombus of smoke.
Behandeling
Opioid analgesia. Anticoagulation: heparin, LMWH; long-term clopidogrel, sometimes aspirin. Oxygen; cautious fluids. Monitor reperfusion injury (hyperkalemia).
Prognose
Poor: high acute mortality/euthanasia; recurrences common.
Preventie
Early cardiac screening; clopidogrel if marked LA enlargement. Treat underlying disease in dogs.
Wanneer de dierenarts bellen
Category-5 emergency: sudden hind-limb paralysis, crying in pain, cold pale paws, severe dyspnea.
Bronnen
- Small Animal Critical Care Medicine, 2nd Edition, p. 253
- Textbook of Veterinary Internal Medicine, 5th Edition, pp. 235, 236, 244
My highlights & notes
Tekenen & symptomen
Rassen met hoger risico
Hoe het wordt gediagnosticeerd
- Abdominal Ultrasonography
- Angiography
- Doppler studies
- Echocardiography
- Measurement of muscle enzymes
- Thoracic radiography
- Thromboelastography
Behandelbenaderingen
Behandeling moet worden voorgeschreven door een bevoegde dierenarts. Specifieke doses worden expres niet getoond.
Veelgestelde vragen
What is Aortic Thromboembolism?
Aortic thromboembolism, or saddle thrombus, is a sudden, life-threatening emergency in dogs and cats where a blood clot blocks blood flow to the hind limbs. This guide explains the causes, critical warning signs, diagnostic process, and intensive treatment options for this severe cardiovascular condition.
What are the symptoms of Aortic Thromboembolism?
Absent arterial pulse、Acute limb paresis、Pain、Posterior paresis、Azotemia (high kidney waste in the blood)、Cool distal limbs、Cyanotic nailbeds、Difficulty breathing (dyspnea)
How is Aortic Thromboembolism diagnosed?
Abdominal Ultrasonography、Angiography、Doppler studies、Echocardiography、Measurement of muscle enzymes、Thoracic radiography
How is Aortic Thromboembolism treated?
Behandeling moet worden voorgeschreven door een bevoegde dierenarts. Specifieke doses worden expres niet getoond.
Bronnen
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 253
- Internal Medicine 5th · p. 236
- Internal Medicine 5th · p. 244
- Internal Medicine 5th · p. 235
- Internal Medicine 5th · p. 236
Dit artikel is algemene educatie en geen vervanging voor professioneel veterinair advies. Bij ziekte: raadpleeg een dierenarts.
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