Spring til indhold
Peqaboo
Åbn Peqaboo
Udforsk Peqaboo

Åbn Peqaboo
Vælg dit sprog

DanskDanmark

Addison Disease

Hypoadrenocorticism

Også kendt som: Hypoadrenocorticism, Addison's disease, Adrenal insufficiency

DyrlægevurderetCatDogHastighed: EmergencyHvor almindeligt: Uncommon

Kort sagt

Addison's disease is an uncommon endocrine disorder where the adrenal glands fail to produce vital hormones. This leads to severe gastrointestinal issues, weakness, and life-threatening electrolyte imbalances. While an Addisonian crisis is a veterinary emergency, the long-term prognosis is excellent with lifelong daily or monthly hormone replacement therapy.

Anatomy diagram showing the location of the adrenal glands near the kidneys in a dog.
The adrenal glands are small but vital organs located just ahead of the kidneys.

TL;DR. Alvorlig men velbehandlet binyrebarkinsufficiens; livslang medicin giver fremragende livskvalitet.

Binyrerne sidder foran nyrerne og danner cortisol og aldosteron.

Hvad er det?

For lidt gluko- og mineralkortikoider. Primært hunde; sjældent hos kat. Uden aldosteron: hyperkaliæmi, hyponatriæmi, hypovolæmi, bradykardi, shock.

Årsager og risikofaktorer

Ofte immunmedieret barkdestruktion. Også iatrogen efter abrupt steroidstop eller overbehandling af Cushing. Raceprædisposition hos nogle hunde.

Tegn at holde øje med

  • Letargi, anoreksi, opkast/diarré, svaghed (hyppige)
  • Dehydrering; bradykardi (lejlighedsvis)
  • Kollaps / hypovolæmisk shock (Addison-krise)

A lethargic Standard Poodle lying down on a living room rug, looking weak and tired.
Letargi og svaghed er hyppige tidlige tegn.

Diagnose

Na:K-ratio, hyperkaliæmi. ACTH-stimulationstest (guldstandard). EKG ved K-arytmier.

A veterinary electrocardiogram monitor displaying abnormal heart rhythms, with no humans visible in the frame.
EKG fanger farlige arytmier fra højt kalium.

Behandling

Krise: aggressive i.v. væsker, Dexamethasone. Vedligehold: DOCP eller Fludrocortisone plus prednison; stressdoser.

Prognose

Fremragende ved stabil livslang terapi.

Forebyggelse

Stop aldrig steroider abrupt. Avlsscreening ved prædisposition.

Hvornår ringe til dyrlægen

Akut: kollaps, ekstrem svaghed, blodig diarré/opkast, blege slimhinder.

Kilder

  • Textbook of Veterinary Internal Medicine, 5th Edition, page 884, 888.
  • Small Animal Critical Care Medicine, 2nd Edition, pages 425, 427.

My highlights & notes

Tegn og symptomer

Racer med højere risiko

Hvordan det diagnosticeres

  • ACTH Stimulation TestGuldstandard
  • Abdominal Ultrasonography
  • Baseline endogenous ACTH concentration
  • Electrocardiogram (ECG)
  • Low-dose ACTH stimulation test
  • Plasma aldosterone concentrations during ACTH stimulation test
  • Radiography
  • Serum electrolyte concentrations (Na:K ratio)

Behandlingsmetoder

Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.

Ofte stillede spørgsmål

What is Addison Disease?

Addison's disease is an uncommon endocrine disorder where the adrenal glands fail to produce vital hormones. This leads to severe gastrointestinal issues, weakness, and life-threatening electrolyte imbalances. While an Addisonian crisis is a veterinary emergency, the long-term prognosis is excellent with lifelong daily or monthly hormone replacement therapy.

What are the symptoms of Addison Disease?

Loss of appetite、Dehydration、Diarrhoea、Lethargy、Vomiting (throwing up)、Weakness (low energy, no strength)、Weight loss (getting thinner)、Hematemesis

How is Addison Disease diagnosed?

ACTH Stimulation Test、Abdominal Ultrasonography、Baseline endogenous ACTH concentration、Electrocardiogram (ECG)、Low-dose ACTH stimulation test、Plasma aldosterone concentrations during ACTH stimulation test

How is Addison Disease treated?

Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.

Kilder

  1. Internal Medicine 5th · p. 884
  2. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 425
  3. Internal Medicine 5th · p. 884
  4. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 427
  5. Internal Medicine 5th · p. 888
  6. Internal Medicine 5th · p. 888

Artiklen er generel oplysning og erstatter ikke dyrlægeråd. Hvis dyret er sygt, kontakt en dyrlæge.

Bekymret for dit dyr?

Peqaboos AI hjælper dig med at følge symptomer, forstå labsvar og vide, hvornår du skal se dyrlægen.

Hent Peqaboo-appen