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Exocrine Pancreatic Insufficiency

Også kjent som: EPI

VeterinærgodkjentCatDogHaster: LowHvor vanlig: Common
Compiled from veterinary literature and clinical references· Updated 2026-07-30·How we create this

Kort fortalt

Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.

Anatomical illustration showing a dog's stomach, small intestine, and the adjacent pancreas.
The pancreas plays a dual role in the body, producing both systemic hormones and essential digestive enzymes.

TL;DR. Kan håndteres: for lite fordøyelsesenzymer; vekttap og diaré til tross for stor appetitt.

Bukspyttkjertelen lager hormoner og enzymer.

Hva er det?

Uten lipase, amylase og proteaser: steatoré og vekttap.

"The pancreas is the only significant source of lipase, so fat maldigestion with fatty feces (steatorrhea) and weight loss are the predominant signs of EPI."

Årsaker og risikofaktorer

Acinær atrofi (PAA) ofte immunmediert (schäfer). Katt: kronisk pankreatitt i sluttstadiet.

Tegn å se etter

  • Vekttap (kardinal)
  • Fet avføring (kardinal)
  • Kronisk diaré (vanlig)
  • Stor appetitt (vanlig)
  • Avmagring, lav B12 (vanlig)

Close-up of an emaciated dog showing visible ribs and a dry, lackluster coat.
Kraftig avmagring og matt pels er typiske.

Hvordan veterinærer diagnostiserer

Serum-TLI fastende: test av valg.

"Measurement of decreased TLI in the blood has a high sensitivity and specificity for the diagnosis of EPI in dogs and cats and is currently the single test of choice for diagnosis in small animals."

A veterinarian in a clinic setting holding a blood tube for diagnostic testing.
TLI er gullstandard.

Behandlingsalternativer

Pankreasenzymer livslangt til hvert måltid.

"All dogs and cats with clinical EPI require enzyme supplementation for the rest of their lives."

Vitamin B12; lettfordøyelig fôr.

Prognose

God ved respons på enzymer og B12.

Forebygging

Ikke avle syke.

Når ringe veterinæren

Igen fet avføring, vektnedgang eller anoreksi: kontakt veterinær.

Kilder

  • Textbook of Veterinary Internal Medicine, 5th Edition, Pages 651, 653, 655.

My highlights & notes

Tegn og symptomer

Weight loss (getting thinner)· Hallmarkfatty feces (steatorrhea)· HallmarkEmaciation· CommonRavenous appetite· Commonchronic diarrhea· Commonhypocobalaminemia· CommonLoss of appetite· OccasionalVomiting (throwing up)· Occasionalchronic seborrheic skin disease· Occasionaldiabetes mellitus· Occasional

Raser med høyere risiko

BoxerCavalier King Charles SpanielChow ChowCollieEnglish Cocker SpanielGerman Shepherd DogGreyhoundRough CollieEngelsk Setter

Hvordan det diagnostiseres

  • Serum trypsin-like immunoreactivity (TLI)Gullstandard
  • Canine pancreatic lipase immunoreactivity (cPLI)
  • Fecal elastase
  • Serum cobalamin concentration
  • Serum folate concentration

Behandlingsmetoder

Cyanocobalamin (Vitamin B12)· Line 1Pancreatic enzyme supplements· Line 1

Behandling må foreskrives av autorisert veterinær. Spesifikke doser vises bevisst ikke.

Vanlige spørsmål

What is Exocrine Pancreatic Insufficiency?

Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.

What are the symptoms of Exocrine Pancreatic Insufficiency?

Weight loss (getting thinner)、fatty feces (steatorrhea)、Emaciation、Ravenous appetite、chronic diarrhea、hypocobalaminemia、Loss of appetite、Vomiting (throwing up)

How is Exocrine Pancreatic Insufficiency diagnosed?

Serum trypsin-like immunoreactivity (TLI)、Canine pancreatic lipase immunoreactivity (cPLI)、Fecal elastase、Serum cobalamin concentration、Serum folate concentration

How is Exocrine Pancreatic Insufficiency treated?

Behandling må foreskrives av autorisert veterinær. Spesifikke doser vises bevisst ikke.

Kilder

  1. Internal Medicine 5th · p. 655
  2. Internal Medicine 5th · p. 651
  3. Internal Medicine 5th · p. 653
  4. Internal Medicine 5th · p. 655
  5. Internal Medicine 5th · p. 653

Artikkelen er generell opplæring og erstatter ikke veterinærråd. Hvis dyret er sykt, kontakt veterinær.

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