Exocrine Pancreatic Insufficiency
Juga dikenal sebagai: EPI
Singkatnya
Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.
TL;DR. Dapat dikelola: enzim pencernaan tidak cukup; turun berat dan diare meski nafsu makan besar.
Pankreas menghasilkan hormon dan enzim.
Apa itu?
Tanpa lipase, amilase, dan protease: steatorea dan penurunan berat.
"The pancreas is the only significant source of lipase, so fat maldigestion with fatty feces (steatorrhea) and weight loss are the predominant signs of EPI."
Penyebab dan faktor risiko
Atrofi asinar (PAA) sering imunomediasi (German Shepherd). Kucing: pankreatitis kronis stadium akhir.
Tanda yang perlu diawasi
- Turun berat (kardinal)
- Feses berminyak (kardinal)
- Diare kronis (sering)
- Nafsu makan besar (sering)
- Kurus, B12 rendah (sering)
Kurus parah dan bulu kusam umum.
Bagaimana dokter hewan mendiagnosis
TLI serum puasa: tes pilihan.
"Measurement of decreased TLI in the blood has a high sensitivity and specificity for the diagnosis of EPI in dogs and cats and is currently the single test of choice for diagnosis in small animals."
TLI adalah baku emas.
Pilihan pengobatan
Enzim seumur hidup setiap makan.
"All dogs and cats with clinical EPI require enzyme supplementation for the rest of their lives."
Vitamin B12; diet mudah dicerna.
Prognosis
Baik jika respons terhadap enzim dan B12.
Pencegahan
Jangan biakkan yang sakit.
Kapan menghubungi dokter hewan
Feses berminyak kembali, turun berat atau anoreksia: hubungi dokter hewan.
Sumber
- Textbook of Veterinary Internal Medicine, 5th Edition, Pages 651, 653, 655.
My highlights & notes
Tanda & gejala
Ras berisiko lebih tinggi
Cara didiagnosis
- Serum trypsin-like immunoreactivity (TLI)Standar emas
- Canine pancreatic lipase immunoreactivity (cPLI)
- Fecal elastase
- Serum cobalamin concentration
- Serum folate concentration
Pendekatan pengobatan
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Pertanyaan umum
What is Exocrine Pancreatic Insufficiency?
Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.
What are the symptoms of Exocrine Pancreatic Insufficiency?
Weight loss (getting thinner)、fatty feces (steatorrhea)、Emaciation、Ravenous appetite、chronic diarrhea、hypocobalaminemia、Loss of appetite、Vomiting (throwing up)
How is Exocrine Pancreatic Insufficiency diagnosed?
Serum trypsin-like immunoreactivity (TLI)、Canine pancreatic lipase immunoreactivity (cPLI)、Fecal elastase、Serum cobalamin concentration、Serum folate concentration
How is Exocrine Pancreatic Insufficiency treated?
Pengobatan harus diresepkan dokter hewan berlisensi. Dosis spesifik sengaja tidak ditampilkan.
Sumber
- Internal Medicine 5th · p. 655
- Internal Medicine 5th · p. 651
- Internal Medicine 5th · p. 653
- Internal Medicine 5th · p. 655
- Internal Medicine 5th · p. 653
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