Exocrine Pancreatic Insufficiency
Også kendt som: EPI
Kort sagt
Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.
TL;DR. Kan håndteres: for få fordøjelsesenzymer; vægttab og diarré trods stor appetit.
Bugspytkirtlen danner hormoner og enzymer.
Hvad er det?
Uden lipase, amylase og proteaser: steatorré og vægttab.
"The pancreas is the only significant source of lipase, so fat maldigestion with fatty feces (steatorrhea) and weight loss are the predominant signs of EPI."
Årsager og risikofaktorer
Acinær atrofi (PAA) ofte immunmedieret (schæfer). Kat: kronisk pankreatitis i slutstadiet.
Tegn at holde øje med
- Vægttab (kardinal)
- Fedtet afføring (kardinal)
- Kronisk diarré (almindelig)
- Stor appetit (almindelig)
- Afmaging, lav B12 (almindelig)
Kraftig afmaging og mat pels er typiske.
Hvordan dyrlæger diagnosticerer
Serum-TLI fastende: test af valg.
"Measurement of decreased TLI in the blood has a high sensitivity and specificity for the diagnosis of EPI in dogs and cats and is currently the single test of choice for diagnosis in small animals."
TLI er guldstandard.
Behandlingsmuligheder
Pankreasenzymer livslangt til hvert måltid.
"All dogs and cats with clinical EPI require enzyme supplementation for the rest of their lives."
Vitamin B12; letfordøjeligt foder.
Prognose
God ved respons på enzymer og B12.
Forebyggelse
Avl ikke syge.
Hvornår ringe til dyrlægen
Igen fedtet afføring, vægttab eller anoreksi: kontakt dyrlæge.
Kilder
- Textbook of Veterinary Internal Medicine, 5th Edition, Pages 651, 653, 655.
My highlights & notes
Tegn og symptomer
Racer med højere risiko
Hvordan det diagnosticeres
- Serum trypsin-like immunoreactivity (TLI)Guldstandard
- Canine pancreatic lipase immunoreactivity (cPLI)
- Fecal elastase
- Serum cobalamin concentration
- Serum folate concentration
Behandlingsmetoder
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Ofte stillede spørgsmål
What is Exocrine Pancreatic Insufficiency?
Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.
What are the symptoms of Exocrine Pancreatic Insufficiency?
Weight loss (getting thinner)、fatty feces (steatorrhea)、Emaciation、Ravenous appetite、chronic diarrhea、hypocobalaminemia、Loss of appetite、Vomiting (throwing up)
How is Exocrine Pancreatic Insufficiency diagnosed?
Serum trypsin-like immunoreactivity (TLI)、Canine pancreatic lipase immunoreactivity (cPLI)、Fecal elastase、Serum cobalamin concentration、Serum folate concentration
How is Exocrine Pancreatic Insufficiency treated?
Behandling skal ordineres af en autoriseret dyrlæge. Specifikke doser vises bevidst ikke.
Kilder
- Internal Medicine 5th · p. 655
- Internal Medicine 5th · p. 651
- Internal Medicine 5th · p. 653
- Internal Medicine 5th · p. 655
- Internal Medicine 5th · p. 653
Artiklen er generel oplysning og erstatter ikke dyrlægeråd. Hvis dyret er sygt, kontakt en dyrlæge.
Bekymret for dit dyr?
Peqaboos AI hjælper dig med at følge symptomer, forstå labsvar og vide, hvornår du skal se dyrlægen.
Hent Peqaboo-appen