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Exocrine Pancreatic Insufficiency

Također poznato kao: EPI

CatDogHitnost: LowKoliko je često: Common

Ukratko

Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.

Anatomical illustration showing a dog's stomach, small intestine, and the adjacent pancreas.
The pancreas plays a dual role in the body, producing both systemic hormones and essential digestive enzymes.

TL;DR. Upravljiva: gušterača ne stvara dovoljno enzima; gubitak težine i proljev unatoč velikom apetitu.

Gušterača stvara hormone i enzime.

Što je to?

Bez lipaze, amilaze i proteaza: steatoreja i gubitak težine.

"The pancreas is the only significant source of lipase, so fat maldigestion with fatty feces (steatorrhea) and weight loss are the predominant signs of EPI."

Uzroci i čimbenici rizika

Acinarna atrofija (PAA) često imunoposredovana (njemački ovčar). Mačka: terminalni kronični pankreatitis.

Znakovi na koje treba paziti

  • Gubitak težine (kardinalno)
  • Masne stolice (kardinalno)
  • Kronični proljev (često)
  • Veliki apetit (često)
  • Mršavost, nizak B12 (često)

Close-up of an emaciated dog showing visible ribs and a dry, lackluster coat.
Izražena mršavost i mat dlaka tipični su.

Kako veterinari dijagnosticiraju

Serumski TLI natašte: test izbora.

"Measurement of decreased TLI in the blood has a high sensitivity and specificity for the diagnosis of EPI in dogs and cats and is currently the single test of choice for diagnosis in small animals."

A veterinarian in a clinic setting holding a blood tube for diagnostic testing.
TLI je zlatni standard.

Opcije liječenja

Pankreasni enzimi doživotno uz svaki obrok.

"All dogs and cats with clinical EPI require enzyme supplementation for the rest of their lives."

Vitamin B12; probavljiva prehrana.

Prognoza

Dobra uz odgovor na enzime i B12.

Prevencija

Ne razmnožavati bolesne.

Kada zvati veterinara

Povrat masnih stolica, gubitak težine ili anoreksija: kontaktirati veterinara.

Izvori

  • Textbook of Veterinary Internal Medicine, 5th Edition, Pages 651, 653, 655.

My highlights & notes

Znakovi i simptomi

Pasmine s višim rizikom

Kako se dijagnosticira

  • Serum trypsin-like immunoreactivity (TLI)Zlatni standard
  • Canine pancreatic lipase immunoreactivity (cPLI)
  • Fecal elastase
  • Serum cobalamin concentration
  • Serum folate concentration

Pristupi liječenju

Liječenje mora propisati licencirani veterinar. Specifične doze namjerno nisu prikazane.

Česta pitanja

What is Exocrine Pancreatic Insufficiency?

Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.

What are the symptoms of Exocrine Pancreatic Insufficiency?

Weight loss (getting thinner)、fatty feces (steatorrhea)、Emaciation、Ravenous appetite、chronic diarrhea、hypocobalaminemia、Loss of appetite、Vomiting (throwing up)

How is Exocrine Pancreatic Insufficiency diagnosed?

Serum trypsin-like immunoreactivity (TLI)、Canine pancreatic lipase immunoreactivity (cPLI)、Fecal elastase、Serum cobalamin concentration、Serum folate concentration

How is Exocrine Pancreatic Insufficiency treated?

Liječenje mora propisati licencirani veterinar. Specifične doze namjerno nisu prikazane.

Izvori

  1. Internal Medicine 5th · p. 655
  2. Internal Medicine 5th · p. 651
  3. Internal Medicine 5th · p. 653
  4. Internal Medicine 5th · p. 655
  5. Internal Medicine 5th · p. 653

Ovaj članak je opća edukacija i ne zamjenjuje veterinarski savjet. Ako je ljubimac bolestan, obratite se veterinaru.

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