Exocrine Pancreatic Insufficiency
Također poznato kao: EPI
Ukratko
Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.

TL;DR. Upravljiva: gušterača ne stvara dovoljno enzima; gubitak težine i proljev unatoč velikom apetitu.
Gušterača stvara hormone i enzime.
Što je to?
Bez lipaze, amilaze i proteaza: steatoreja i gubitak težine.
"The pancreas is the only significant source of lipase, so fat maldigestion with fatty feces (steatorrhea) and weight loss are the predominant signs of EPI."
Uzroci i čimbenici rizika
Acinarna atrofija (PAA) često imunoposredovana (njemački ovčar). Mačka: terminalni kronični pankreatitis.
Znakovi na koje treba paziti
- Gubitak težine (kardinalno)
- Masne stolice (kardinalno)
- Kronični proljev (često)
- Veliki apetit (često)
- Mršavost, nizak B12 (često)

Izražena mršavost i mat dlaka tipični su.
Kako veterinari dijagnosticiraju
Serumski TLI natašte: test izbora.
"Measurement of decreased TLI in the blood has a high sensitivity and specificity for the diagnosis of EPI in dogs and cats and is currently the single test of choice for diagnosis in small animals."

TLI je zlatni standard.
Opcije liječenja
Pankreasni enzimi doživotno uz svaki obrok.
"All dogs and cats with clinical EPI require enzyme supplementation for the rest of their lives."
Vitamin B12; probavljiva prehrana.
Prognoza
Dobra uz odgovor na enzime i B12.
Prevencija
Ne razmnožavati bolesne.
Kada zvati veterinara
Povrat masnih stolica, gubitak težine ili anoreksija: kontaktirati veterinara.
Izvori
- Textbook of Veterinary Internal Medicine, 5th Edition, Pages 651, 653, 655.
My highlights & notes
Znakovi i simptomi
Pasmine s višim rizikom
Kako se dijagnosticira
- Serum trypsin-like immunoreactivity (TLI)Zlatni standard
- Canine pancreatic lipase immunoreactivity (cPLI)
- Fecal elastase
- Serum cobalamin concentration
- Serum folate concentration
Pristupi liječenju
Liječenje mora propisati licencirani veterinar. Specifične doze namjerno nisu prikazane.
Česta pitanja
What is Exocrine Pancreatic Insufficiency?
Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.
What are the symptoms of Exocrine Pancreatic Insufficiency?
Weight loss (getting thinner)、fatty feces (steatorrhea)、Emaciation、Ravenous appetite、chronic diarrhea、hypocobalaminemia、Loss of appetite、Vomiting (throwing up)
How is Exocrine Pancreatic Insufficiency diagnosed?
Serum trypsin-like immunoreactivity (TLI)、Canine pancreatic lipase immunoreactivity (cPLI)、Fecal elastase、Serum cobalamin concentration、Serum folate concentration
How is Exocrine Pancreatic Insufficiency treated?
Liječenje mora propisati licencirani veterinar. Specifične doze namjerno nisu prikazane.
Izvori
- Internal Medicine 5th · p. 655
- Internal Medicine 5th · p. 651
- Internal Medicine 5th · p. 653
- Internal Medicine 5th · p. 655
- Internal Medicine 5th · p. 653
Ovaj članak je opća edukacija i ne zamjenjuje veterinarski savjet. Ako je ljubimac bolestan, obratite se veterinaru.
Zabrinuti za ljubimca?
Peqaboo AI pomaže pratiti simptome, razumjeti laboratorijske nalaze i znati kada posjetiti veterinara.
Preuzmite Peqaboo app