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Exocrine Pancreatic Insufficiency

También conocido como: EPI

CatDogUrgencia: LowFrecuencia: Common

En resumen

Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.

Anatomical illustration showing a dog's stomach, small intestine, and the adjacent pancreas.
The pancreas plays a dual role in the body, producing both systemic hormones and essential digestive enzymes.

TL;DR. El páncreas no produce enzimas digestivas; se controla con enzimas de por vida.

El páncreas fabrica hormonas y enzimas.

¿Qué es?

Sin enzimas: esteatorrea y pérdida de peso.

"The pancreas is the only significant source of lipase, so fat maldigestion with fatty feces (steatorrhea) and weight loss are the predominant signs of EPI."

Causas y factores de riesgo

PAA en perros (pastor alemán); pancreatitis crónica en gatos.

Signos a vigilar

  • Pérdida de peso
  • Heces grasas
  • Diarrea crónica
  • Apetito excesivo
  • Bajo B12

Close-up of an emaciated dog showing visible ribs and a dry, lackluster coat.
El adelgazamiento marcado es clave.

Cómo lo diagnostican los veterinarios

TLI en ayunas.

"Measurement of decreased TLI in the blood has a high sensitivity and specificity for the diagnosis of EPI in dogs and cats and is currently the single test of choice for diagnosis in small animals."

A veterinarian in a clinic setting holding a blood tube for diagnostic testing.
El TLI confirma el diagnóstico.

Opciones de tratamiento

Enzimas con cada comida de por vida.

"All dogs and cats with clinical EPI require enzyme supplementation for the rest of their lives."

B12; dieta digestible.

Pronóstico

Bueno con tratamiento constante.

Prevención

No reproducir afectados.

Cuándo llamar al veterinario

Diarrea grasa de nuevo, baja de peso o anorexia: ver al veterinario.

Fuentes

  • Textbook of Veterinary Internal Medicine, 5th Edition, Pages 651, 653, 655.

My highlights & notes

Signos y síntomas

Razas de mayor riesgo

Cómo se diagnostica

  • Serum trypsin-like immunoreactivity (TLI)Estándar de referencia
  • Canine pancreatic lipase immunoreactivity (cPLI)
  • Fecal elastase
  • Serum cobalamin concentration
  • Serum folate concentration

Enfoques de tratamiento

El tratamiento debe recetarlo un veterinario colegiado según tu mascota. Las dosis concretas no se muestran a propósito.

Preguntas frecuentes

What is Exocrine Pancreatic Insufficiency?

Exocrine pancreatic insufficiency (EPI) is a common gastrointestinal disorder in dogs and cats caused by a deficiency of digestive enzymes. Learn about the cardinal signs like weight loss and chronic diarrhea, how veterinarians diagnose the condition using the gold-standard TLI test, and the lifelong treatment strategies required to help your pet thrive.

What are the symptoms of Exocrine Pancreatic Insufficiency?

Weight loss (getting thinner)、fatty feces (steatorrhea)、Emaciation、Ravenous appetite、chronic diarrhea、hypocobalaminemia、Loss of appetite、Vomiting (throwing up)

How is Exocrine Pancreatic Insufficiency diagnosed?

Serum trypsin-like immunoreactivity (TLI)、Canine pancreatic lipase immunoreactivity (cPLI)、Fecal elastase、Serum cobalamin concentration、Serum folate concentration

How is Exocrine Pancreatic Insufficiency treated?

El tratamiento debe recetarlo un veterinario colegiado según tu mascota. Las dosis concretas no se muestran a propósito.

Fuentes

  1. Internal Medicine 5th · p. 655
  2. Internal Medicine 5th · p. 651
  3. Internal Medicine 5th · p. 653
  4. Internal Medicine 5th · p. 655
  5. Internal Medicine 5th · p. 653

Este artículo es educación general y no sustituye el consejo veterinario profesional. Si tu mascota está mal, consulta a un veterinario.

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