Insulinoma
Pancreatic β-cell tumor
Juga dikenali sebagai: β-cell tumor, beta-cell tumor, functional islet cell adenocarcinoma, pancreatic neuroendocrine tumor, NETP
Ringkasnya
An insulinoma is a functional tumor of the pancreatic beta cells that secretes excess insulin, causing severe low blood sugar (hypoglycemia). Learn about the symptoms, diagnostic tests, and treatment options to help manage this complex endocrine disease.
TL;DR. Tumor pankreas yang melepaskan insulin dan menyebabkan hipoglisemia teruk: kelemahan, rebah, sawan.
Feret kerap terjejas.
Apakah ia?
Tumor sel beta dengan rembesan insulin tanpa kawalan, glukosa rendah dan otak kekurangan tenaga.
Punca dan faktor risiko
Neoplasia; predisposisi German Shepherd, Labrador, Golden, Boxer, Cocker, Siamese. Pada feret kerap.
Tanda
- Kelemahan dan sawan (kardinal)
- Rebah, ataksia, letargi
- Tingkah laku pelik, menggeletar, polifagia
Kelemahan dan letargi adalah tanda awal.
Diagnosis
Insulin serum semasa hipoglisemia didokumen; fruktosamin rendah; CT/ultrasound; eksplorasi pembedahan.
Imej membantu mencari tumor.
Rawatan
Kecemasan: dekstros dan glukokortikoid. Pembedahan diutamakan. Perubatan: diazoksida, oktreotida, streptozosin, makan kerap.
Prognosis
Sembuh jarang; dengan bedah dan ubat selalunya hidup lebih lama.
Pencegahan
Tiada pencegahan primer; glukosa pada senior berisiko.
Bila hubungi doktor haiwan
Sawan, rebah, kelemahan ekstrem: kecemasan. Sirap pada gusi hanya jika sedar.
Sumber
- Small Animal Internal Medicine, 5th Edition.
- Small Animal Critical Care Medicine, 2nd Edition.
My highlights & notes
Tanda & simptom
Baka berisiko lebih tinggi
Cara didiagnosis
- Serum insulin concentration during hypoglycemiaStandard emas
- Abdominal Ultrasonography
- Amended insulin-to-glucose ratio (AIGR)
- Computed Tomography (CT)
- Fasting with hourly blood glucose evaluations
- Laparotomy / Surgical exploration
- Low fructosamine values
- Thoracic radiographs
Pendekatan rawatan
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Soalan lazim
What is Insulinoma?
An insulinoma is a functional tumor of the pancreatic beta cells that secretes excess insulin, causing severe low blood sugar (hypoglycemia). Learn about the symptoms, diagnostic tests, and treatment options to help manage this complex endocrine disease.
What are the symptoms of Insulinoma?
Seizures、Weakness (low energy, no strength)、Ataxia (wobbly, unsteady walking)、Lethargy、Collapse (suddenly going down)、Bizarre behavior、Facial paresis、Muscle atrophy
How is Insulinoma diagnosed?
Serum insulin concentration during hypoglycemia、Abdominal Ultrasonography、Amended insulin-to-glucose ratio (AIGR)、Computed Tomography (CT)、Fasting with hourly blood glucose evaluations、Laparotomy / Surgical exploration
How is Insulinoma treated?
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Sumber
- Internal Medicine 5th · p. 850
- Internal Medicine 5th · p. 850
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 394
- Internal Medicine 5th · p. 851
- Cowell and Tyler s Diagnostic Cytology and Hematology of the Dog and Cat, 5th Edition (VetBooks.ir) · p. 340
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 395
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