Canine Distemper
Canine distemper virus
Juga dikenali sebagai: CDV Infection, Canine Distemper Virus Infection, Hard pad disease
Ringkasnya
Canine distemper is a highly contagious, severe viral disease affecting dogs and ferrets. It attacks multiple body systems, including the respiratory, gastrointestinal, and nervous systems, often leading to irreversible neurological damage. Understanding its signs, diagnostic process, and the critical importance of vaccination is essential for every pet owner.

TL;DR. Jangkitan virus sangat berjangkit dan mengancam nyawa pada anjing dan feret, merosakkan saluran pernafasan, gastrousus dan saraf; sering meninggalkan kesan neurologi kekal.
Penyakit sistemik teruk dengan letargi ketara.
Apakah ia?
Morbillivirus (CDV). Menyerang tisu limfoid, saraf dan epitelium. Fasa: limfopenia/demam, kemudian saluran nafas/GI/kulit/mata, sering CNS. Tiada antivirus penyembuh.
Punca dan faktor risiko
Aerosol dan cecair badan.
"CDV is shed in respiratory secretions for up to 90 days after infection. Initial replication of CDV is in lymphoid tissue, and viral destruction of lymphocytes results in lymphopenia and pyrexia."
Anak anjing tidak divaksin 6-12 minggu risiko tertinggi; feret hampir 100% maut. Tiada predisposisi baka.
Tanda
- Mioklonus (kardinal)
- Biasa: demam, kemurungan, rembesan hidung mukopurulen, batuk, muntah/cirit-birit, pustul, hiperkeratosis (hard pad), sawan, ataksia
- Kadang-kadang: uveitis, neuritis optik, KCS, hipoplasia enamel

Hiperkeratosis pad kaki adalah klasik.
Diagnosis
CBC (limfopenia), radiograf toraks, sitologi konjunktiva, RT-PCR (piawai emas), IHC, kadang CSF.

Radiograf toraks menilai pneumonia sekunder.
Rawatan
Hanya sokongan: cecair IV, antibiotik jangkitan sekunder, terapi pernafasan, antiemetik, antikonvulsan. Glucocorticoids secara terpilih. Pengasingan ketat.
Prognosis
Sering buruk, terutamanya tanda CNS.
"CNS disease is generally progressive and carries a poor prognosis; it can develop in some dogs that never had systemic signs of disease recognized."
Pencegahan
Vaksin teras anak anjing + booster; vaksin khusus feret; kuarantin; disinfeksi.
Bila hubungi doktor haiwan
Kecemasan: sawan/mioklonus; sesak nafas teruk; rembesan kuning-hijau; rebah; tanda GI teruk; buta mendadak.
Sumber
- Textbook of Veterinary Internal Medicine, 5th Edition, pages 1077, 1375
- Small Animal Critical Care Medicine, 2nd Edition, page 561
My highlights & notes
Tanda & simptom
Cara didiagnosis
- Cerebrospinal fluid (CSF) analysis
- Complete Blood Count (CBC)
- Cytologic examination of conjunctival scrapings
- Immunohistochemistry (IHC) on biopsies
- Reverse transcriptase-polymerase chain reaction (RT-PCR)
- Thoracic radiography
Pendekatan rawatan
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Soalan lazim
What is Canine Distemper?
Canine distemper is a highly contagious, severe viral disease affecting dogs and ferrets. It attacks multiple body systems, including the respiratory, gastrointestinal, and nervous systems, often leading to irreversible neurological damage. Understanding its signs, diagnostic process, and the critical importance of vaccination is essential for every pet owner.
What are the symptoms of Canine Distemper?
Myoclonus、Loss of appetite、Ataxia (wobbly, unsteady walking)、Low mood and dullness、Diarrhoea、Enamel hypoplasia、Fever、Hyperkeratosis of the nose and footpads
How is Canine Distemper diagnosed?
Cerebrospinal fluid (CSF) analysis、Complete Blood Count (CBC)、Cytologic examination of conjunctival scrapings、Immunohistochemistry (IHC) on biopsies、Reverse transcriptase-polymerase chain reaction (RT-PCR)、Thoracic radiography
How is Canine Distemper treated?
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Sumber
- Internal Medicine 5th · p. 1375
- Internal Medicine 5th · p. 1375
- Internal Medicine 5th · p. 1077
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 561
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 561
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