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Feline Infectious Peritonitis

Feline Infectious Peritonitis

Juga dikenali sebagai: FIP

Disemak doktor haiwanCatKecemasan: HighSeberapa biasa: Uncommon
Compiled from veterinary literature and clinical references· Updated 2026-07-30·How we create this

Ringkasnya

Feline Infectious Peritonitis (FIP) is an uncommon but serious viral disease in cats caused by a mutation of the common feline coronavirus. It occurs in "wet" (effusive) and "dry" (noneffusive) forms, causing progressive inflammation throughout the body. While historically considered fatal, understanding the diagnostic process and supportive care options is crucial for managing affected cats.

A domestic cat sitting quietly, looking slightly lethargic.
FIP often begins with vague signs such as lethargy, decreased appetite, and weight loss.

TL;DR. Penyakit virus progresif akibat mutasi coronavirus kucing biasa; bentuk «basah» (cecair) atau «kering» (granuloma organ).

FIP sering bermula dengan tanda kabur: lethargi, kurang selera, susut berat.

Apakah itu?

Penyakit sistemik tidak biasa. FCoV meluas dan biasanya ringan. Sebilangan kecil bermutasi kepada FIPV dalam makrofaj dengan keradangan teruk.

  • Efusi («basah»): vaskulitis dan cecair kuning kaya protein.
  • Bukan efusi («kering»): piogranuloma di ginjal, hati, nodus, mata, CNS.

Punca dan faktor risiko

Mutasi dalam individu; FIP sendiri jarang menjangkiti kucing-ke-kucing (FCoV ya, najis). Risiko: <2 tahun atau sangat tua; stres; baka British Shorthair, Devon Rex, Abyssinian.

Tanda yang perlu diperhatikan

  • Lazim: susut berat, demam turun naik, anoreksia, lethargi
  • Kadang-kadang: perut buncit, sesak nafas, jaundis, uveitis, ataksia, nistagmus/sawan, muntah/cirit

A close-up of a cat's eye showing anterior uveitis, with cloudiness and inflammation.
Uveitis anterior ialah tanda kadang-kadang FIP kering.

Bagaimana doktor haiwan mendiagnosis

Diagnosis sukar. Darah: globulin tinggi, albumin rendah, A:G rendah. Basah: Rivalta, RT-PCR, imunostitokimia. Kering: imej + biopsi. Titer Ab = pendedahan sahaja. Piawaian emas: histopatologi + imunostaining.

Pilihan rawatan

Historinya hampir selalu fatal tanpa antivirus moden. Paliatif glukokortikoid; interferon omega; sokongan. Ketersediaan GS-441524 berbeza mengikut wilayah.

Prognosis

Buruk tanpa terapi antivirus lanjutan; basah lebih cepat. Lebih baik di mana antivirus moden ada.

Pencegahan

Kebersihan rumah multi-kucing, kurang stres. Pengasingan kerana «jangkitan FIP» tidak diperlukan menurut rujukan.

Bila hubungi doktor haiwan

Kecemasan: sesak nafas, sawan, anoreksia >24-48 j, lemah melampau, jaundis ketara.

Sumber

  • Small Animal Critical Care Medicine, pp. 564
  • Internal Medicine, pp. 1378, 1380

My highlights & notes

Tanda & simptom

Loss of appetite· CommonFever· CommonLethargy· CommonWeight loss (getting thinner)· CommonBloated belly· OccasionalInflammation inside the eye (anterior uveitis)· OccasionalAtaxia (wobbly, unsteady walking)· OccasionalChorioretinitis· OccasionalDiarrhoea· OccasionalDifficulty breathing (dyspnea)· OccasionalYellowing of the skin and eyes (jaundice)· OccasionalIridocyclitis· OccasionalEye flicking· OccasionalEnlarged kidney· OccasionalSeizures· OccasionalEnlarged spleen· OccasionalVomiting (throwing up)· Occasional

Baka berisiko lebih tinggi

Kucing AbyssinianBritish ShorthairDevon Rex

Cara didiagnosis

  • Histopathologic examination of biopsy specimens with immunostainingStandard emas
  • Coronavirus antibody titer
  • Effusion ̳-globulin concentration
  • Immunocytochemistry on macrophages in effusion fluid
  • RT-PCR on pleural or peritoneal exudate
  • Rivalta test
  • Serum or effusion albumin-to-globulin ratio

Pendekatan rawatan

Glucocorticoids· Line 1Interferon Omega· Line 2Ascorbic AcidAspirinPropentofyllineStanozolol

Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.

Soalan lazim

What is Feline Infectious Peritonitis?

Feline Infectious Peritonitis (FIP) is an uncommon but serious viral disease in cats caused by a mutation of the common feline coronavirus. It occurs in "wet" (effusive) and "dry" (noneffusive) forms, causing progressive inflammation throughout the body. While historically considered fatal, understanding the diagnostic process and supportive care options is crucial for managing affected cats.

What are the symptoms of Feline Infectious Peritonitis?

Loss of appetite、Fever、Lethargy、Weight loss (getting thinner)、Bloated belly、Inflammation inside the eye (anterior uveitis)、Ataxia (wobbly, unsteady walking)、Chorioretinitis

How is Feline Infectious Peritonitis diagnosed?

Histopathologic examination of biopsy specimens with immunostaining、Coronavirus antibody titer、Effusion ̳-globulin concentration、Immunocytochemistry on macrophages in effusion fluid、RT-PCR on pleural or peritoneal exudate、Rivalta test

How is Feline Infectious Peritonitis treated?

Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.

Sumber

  1. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 564
  2. Internal Medicine 5th · p. 1380
  3. Internal Medicine 5th · p. 1378
  4. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 564

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