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Feline Infectious Peritonitis

Feline Infectious Peritonitis

Također poznato kao: FIP

CatHitnost: HighKoliko je često: Uncommon
Compiled from veterinary literature and clinical references· Updated 2026-07-28·How we create this

Ukratko

Feline Infectious Peritonitis (FIP) is an uncommon but serious viral disease in cats caused by a mutation of the common feline coronavirus. It occurs in "wet" (effusive) and "dry" (noneffusive) forms, causing progressive inflammation throughout the body. While historically considered fatal, understanding the diagnostic process and supportive care options is crucial for managing affected cats.

A domestic cat sitting quietly, looking slightly lethargic.
FIP often begins with vague signs such as lethargy, decreased appetite, and weight loss.

TL;DR. Progresivna virusna bolest mutacije uobičajenog mačjeg koronavirusa; «vlažni» (tekućina) ili «suhi» (organski granulomi).

FIP često počinje nejasnim znakovima: letargija, manji apetit, gubitak težine.

Što je to?

Neuobičajena sistemska bolest. FCoV je raširen i često blag. U malog broja mutacija u FIPV u makrofagima s teškom upalom.

  • Efuzivni («vlažni»): vaskulitis i žuta tekućina bogata proteinima.
  • Neefuzivni («suhi»): piogranulomi u bubrezima, jetri, limfnim čvorovima, oku, CNS-u.

Uzroci i čimbenici rizika

Mutacija u jedinki; FIP se ne širi lako mačka-mačka (FCoV da, feces). Rizik: <2 godine ili vrlo stari; stres; pasmine British Shorthair, Devon Rex, Abyssinian.

Znakovi

  • Česti: gubitak težine, fluktuirajuća vrućica, anoreksija, letargija
  • Povremeni: nadut trbuh, dispneja, ikterus, uveitis, ataksija, nistagmus/konvulzije, povraćanje/proljev

A close-up of a cat's eye showing anterior uveitis, with cloudiness and inflammation.
Prednji uveitis je povremeni znak suhog FIP-a.

Kako veterinari dijagnosticiraju

Teška dijagnoza. Krv: visoki globulini, niski albumin, niski A:G. Vlažni: Rivalta, RT-PCR, imunocitokemija. Suhi: slikovna + biopsija. Titar Ab = samo izloženost. Zlatni standard: histopatologija s imunoboanjem.

Liječenje

Povijesno gotovo uvijek fatalan bez modernih antivirusnih. Palijativno glukokortikoidi; interferon omega; potpora. Dostupnost GS-441524 ovisi o regiji.

Prognoza

Loša bez napredne antivirusne terapije; vlažni brži. Bolja gdje su moderni antivirusni dostupni.

Prevencija

Higijena u domovima s više mačaka, manje stresa. Izolacija zbog «zaraze FIP-om» prema izvorima nije potrebna.

Kada zvati veterinara

Hitno: otežano disanje, konvulzije, anoreksija >24-48 h, ekstremna slabost, izražen ikterus.

Izvori

  • Small Animal Critical Care Medicine, pp. 564
  • Internal Medicine, pp. 1378, 1380

My highlights & notes

Znakovi i simptomi

Loss of appetite· CommonFever· CommonLethargy· CommonWeight loss (getting thinner)· CommonBloated belly· OccasionalInflammation inside the eye (anterior uveitis)· OccasionalAtaxia (wobbly, unsteady walking)· OccasionalChorioretinitis· OccasionalDiarrhoea· OccasionalDifficulty breathing (dyspnea)· OccasionalYellowing of the skin and eyes (jaundice)· OccasionalIridocyclitis· OccasionalEye flicking· OccasionalEnlarged kidney· OccasionalSeizures· OccasionalEnlarged spleen· OccasionalVomiting (throwing up)· Occasional

Pasmine s višim rizikom

AbyssinianBritish ShorthairDevon Rex

Kako se dijagnosticira

  • Histopathologic examination of biopsy specimens with immunostainingZlatni standard
  • Coronavirus antibody titer
  • Effusion ̳-globulin concentration
  • Immunocytochemistry on macrophages in effusion fluid
  • RT-PCR on pleural or peritoneal exudate
  • Rivalta test
  • Serum or effusion albumin-to-globulin ratio

Pristupi liječenju

Glucocorticoids· Line 1Interferon Omega· Line 2Ascorbic AcidAspirinPropentofyllineStanozolol

Liječenje mora propisati licencirani veterinar. Specifične doze namjerno nisu prikazane.

Česta pitanja

What is Feline Infectious Peritonitis?

Feline Infectious Peritonitis (FIP) is an uncommon but serious viral disease in cats caused by a mutation of the common feline coronavirus. It occurs in "wet" (effusive) and "dry" (noneffusive) forms, causing progressive inflammation throughout the body. While historically considered fatal, understanding the diagnostic process and supportive care options is crucial for managing affected cats.

What are the symptoms of Feline Infectious Peritonitis?

Loss of appetite、Fever、Lethargy、Weight loss (getting thinner)、Bloated belly、Inflammation inside the eye (anterior uveitis)、Ataxia (wobbly, unsteady walking)、Chorioretinitis

How is Feline Infectious Peritonitis diagnosed?

Histopathologic examination of biopsy specimens with immunostaining、Coronavirus antibody titer、Effusion ̳-globulin concentration、Immunocytochemistry on macrophages in effusion fluid、RT-PCR on pleural or peritoneal exudate、Rivalta test

How is Feline Infectious Peritonitis treated?

Liječenje mora propisati licencirani veterinar. Specifične doze namjerno nisu prikazane.

Izvori

  1. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 564
  2. Internal Medicine 5th · p. 1380
  3. Internal Medicine 5th · p. 1378
  4. Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 564

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