Buprenorphine
別名: Buprenex, Subutex, Suboxone, Butrans, Temgesic, Simbadol, Zorbium, Bupaq, Buprecare, Buprenodale, Buprevet, Vetergesic
Buprenorphine is a potent pain reliever that is often sent home for use in cats and small dogs. * **Administration Technique**: If you are instructed to give this medication by mouth, **do not squirt it down the throat**. Instead, place the tip of the syringe into the side of the mouth (the cheek pouch or under the tongue) and administer the liquid. The drug is absorbed directly through the gums. If swallowed, it is largely destroyed by the liver before it can work. * **Preparation**: Pre-measuring dosages in syringes is highly recommended to ensure accurate dosing at home. * **What to Expect**: Your pet may become slightly sleepy or, less commonly, a bit restless or vocal. * **Safety**: This medication is very safe when used as directed, but it is a controlled substance. Keep it strictly out of reach of children and other pets.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Analgesia
- Analgesia
- Analgesia
- Analgesia
- Analgesia
- Analgesia
- Analgesia
- Analgesia
- Analgesia
- Analgesia
- Analgesia in the emergent patient
- Analgesia
- Neuroleptanalgesia
- Neuroleptanalgesia
- Analgesia (acute or chronic visceral pain)
給藥方式
可能的副作用
- Respiratory depression (rare but significant)
- Sedation
- Urine retention or difficulty voiding (particularly with high IV or epidural doses)
- Excitement (horses)
- Diminished gut sounds (horses)
- Vomiting (rare in cats)
注意事項與禁忌
- Known hypersensitivity to buprenorphine
- Use with caution in patients with hypothyroidism, severe renal insufficiency, adrenocortical insufficiency (Addison's), and in geriatric or severely debilitated patients. Use cautiously in patients with compromised cardiopulmonary function due to the rare risk of respiratory depression. Extreme caution is required in patients with head trauma, increased CSF pressure, or CNS dysfunction (e.g., coma). Patients with severe hepatic dysfunction may eliminate the drug more slowly. May increase bile duct pressure; use cautiously in biliary tract disease.
藥物相互作用
- Local Anesthetics (mepivacaine, bupivacaine): May be potentiated by concomitant use of buprenorphine
- Anticonvulsants (phenobarbital, phenytoin): May decrease plasma buprenorphine levels
- Benzodiazepines: Case reports of humans developing respiratory/cardiovascular/CNS depression; use with caution
- CNS Depressants (anesthetics, antihistamines, phenothiazines, barbiturates, alcohol): May cause increased CNS or respiratory depression when used with buprenorphine
- Erythromycin: Can increase plasma buprenorphine levels
- Fentanyl (and other pure opiate agonists): Buprenorphine may potentially antagonize some analgesic effects, but may also reverse some sedative and respiratory depressant effects
- Halothane: Potentially can increase buprenorphine effects
- Azole Antifungals (ketoconazole, itraconazole, fluconazole): Can increase plasma buprenorphine levels
- Monoamine Oxidase Inhibitors (selegiline, amitraz): Possible additive effects or increased CNS depression
- Naloxone: May reduce analgesia associated with high dose buprenorphine
常見問題
Buprenorphine用於寵物有甚麼用途？
Buprenorphine is a potent pain reliever that is often sent home for use in cats and small dogs. * **Administration Technique**: If you are instructed to give this medication by mouth, **do not squirt it down the throat**. Instead, place the tip of the syringe into the side of the mouth (the cheek pouch or under the tongue) and administer the liquid. The drug is absorbed directly through the gums. If swallowed, it is largely destroyed by the liver before it can work. * **Preparation**: Pre-measuring dosages in syringes is highly recommended to ensure accurate dosing at home. * **What to Expect**: Your pet may become slightly sleepy or, less commonly, a bit restless or vocal. * **Safety**: This medication is very safe when used as directed, but it is a controlled substance. Keep it strictly out of reach of children and other pets.
Buprenorphine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。