Metabolic Bone Disease
Nutritional secondary hyperparathyroidism
Ook bekend als: Nutritional Secondary Hyperparathyroidism, NSHP, Fibrous Osteodystrophy, Osteomalacia, Rickets
Kort samengevat
Metabolic Bone Disease (MBD), or nutritional secondary hyperparathyroidism, is a common and serious condition in captive reptiles and turtles. Caused by a lack of dietary calcium, improper calcium-to-phosphorus ratios, or insufficient UVB light, it leads to weak, deformed bones and muscle tremors. Learn how to recognize the signs, how veterinarians diagnose and treat it, and how proper husbandry can prevent this debilitating disease.

TL;DR. Voorkombare aandoening bij reptielen en schildpadden door calcium- of UVB-tekort: zachte botten, misvormingen en trillingen.
UVB-licht is essentieel voor vitamine D3-synthese en calciumopname.
Wat is het?
Metabolic bone disease in captive reptiles/turtles is usually nutritional secondary hyperparathyroidism: insufficient calcium or UVB leads to soft bones, fibrous reinforcement of limbs/jaws, and muscle tremors. Calcium is pulled from bone to keep blood calcium safe.
Oorzaken en risicofactoren
Husbandry errors: inadequate UVB (290-315 nm), low dietary calcium, poor Ca:P ratio (aim near 2:1), cold enclosures. Fast-growing species are highest risk.
Signalen
- Rubber jaw; soft/warped shell in chelonians (cardinal)
- Swollen firm limbs, pathological fractures, lethargy, anorexia, tremors (common)
- Paresis/paralysis from spinal deformity (occasional)

Verkorte kaak en gezwollen poten zijn klassieke late tekenen.
Diagnostiek
Husbandry review. Radiographs (gold): demineralized ghost bones, hidden fractures. Ionized calcium; biochemistry for kidney and phosphorus.

Röntgen toont ontkalkte botten en verborgen fracturen.
Behandeling
Oral or injectable calcium salts; phosphate binders if phosphorus high; cautious calcitriol after calcium stabilizes. Fix UVB, heat gradient, diet.
Prognose
Excellent if early before severe deformity. Permanent shape changes may remain. Poor with paralysis or severe kidney disease.
Preventie
Linear UVB (replace every 6-12 months), calcium (± D3 indoors), gut-load insects, Ca-rich greens, correct thermal gradient.
Wanneer de dierenarts bellen
Emergency: continuous tremors/seizures, inability to lift body, soft jaw/shell, visible fractures, extreme lethargy or prolonged anorexia.
Bronnen
- Mader's Reptile and Amphibian Medicine and Surgery, 3rd Edition, pages 315-321, 811-814.
- BSAVA Manual of Reptiles, 3rd Edition, pages 102-105, 210-212.
My highlights & notes
Tekenen & symptomen
Hoe het wordt gediagnosticeerd
- RadiographyGouden standaard
- Plasma Biochemistry Panel
- Plasma Ionized Calcium
Behandelbenaderingen
Behandeling moet worden voorgeschreven door een bevoegde dierenarts. Specifieke doses worden expres niet getoond.
Veelgestelde vragen
What is Metabolic Bone Disease?
Metabolic Bone Disease (MBD), or nutritional secondary hyperparathyroidism, is a common and serious condition in captive reptiles and turtles. Caused by a lack of dietary calcium, improper calcium-to-phosphorus ratios, or insufficient UVB light, it leads to weak, deformed bones and muscle tremors. Learn how to recognize the signs, how veterinarians diagnose and treat it, and how proper husbandry can prevent this debilitating disease.
What are the symptoms of Metabolic Bone Disease?
Soft, deformed carapace or plastron、Soft, pliable mandible or maxilla (rubber jaw)、Loss of appetite、Lethargy and weakness、Muscle tremors or twitching、Pathological fractures、Swollen, firm limbs、Paresis or paralysis
How is Metabolic Bone Disease diagnosed?
Radiography、Plasma Biochemistry Panel、Plasma Ionized Calcium
How is Metabolic Bone Disease treated?
Behandeling moet worden voorgeschreven door een bevoegde dierenarts. Specifieke doses worden expres niet getoond.
Dit artikel is algemene educatie en geen vervanging voor professioneel veterinair advies. Bij ziekte: raadpleeg een dierenarts.
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