Metabolic Bone Disease
Nutritional secondary hyperparathyroidism
Nota anche come: Nutritional Secondary Hyperparathyroidism, NSHP, Fibrous Osteodystrophy, Osteomalacia, Rickets
In breve
Metabolic Bone Disease (MBD), or nutritional secondary hyperparathyroidism, is a common and serious condition in captive reptiles and turtles. Caused by a lack of dietary calcium, improper calcium-to-phosphorus ratios, or insufficient UVB light, it leads to weak, deformed bones and muscle tremors. Learn how to recognize the signs, how veterinarians diagnose and treat it, and how proper husbandry can prevent this debilitating disease.

TL;DR. Condizione prevenibile in rettili e tartarughe da carenza di calcio o UVB: ossa molli, deformità e tremori.
La luce UVB è essenziale per sintetizzare vitamina D3 e assorbire calcio.
Cos'è?
Metabolic bone disease in captive reptiles/turtles is usually nutritional secondary hyperparathyroidism: insufficient calcium or UVB leads to soft bones, fibrous reinforcement of limbs/jaws, and muscle tremors. Calcium is pulled from bone to keep blood calcium safe.
Cause e fattori di rischio
Husbandry errors: inadequate UVB (290-315 nm), low dietary calcium, poor Ca:P ratio (aim near 2:1), cold enclosures. Fast-growing species are highest risk.
Segni da osservare
- Rubber jaw; soft/warped shell in chelonians (cardinal)
- Swollen firm limbs, pathological fractures, lethargy, anorexia, tremors (common)
- Paresis/paralysis from spinal deformity (occasional)

Mascella accorciata e arti gonfi sono segni avanzati classici.
Come diagnosticano i veterinari
Husbandry review. Radiographs (gold): demineralized ghost bones, hidden fractures. Ionized calcium; biochemistry for kidney and phosphorus.

Le radiografie mostrano ossa demineralizzate e fratture nascoste.
Opzioni di trattamento
Oral or injectable calcium salts; phosphate binders if phosphorus high; cautious calcitriol after calcium stabilizes. Fix UVB, heat gradient, diet.
Prognosi
Excellent if early before severe deformity. Permanent shape changes may remain. Poor with paralysis or severe kidney disease.
Prevenzione
Linear UVB (replace every 6-12 months), calcium (± D3 indoors), gut-load insects, Ca-rich greens, correct thermal gradient.
Quando chiamare il veterinario
Emergency: continuous tremors/seizures, inability to lift body, soft jaw/shell, visible fractures, extreme lethargy or prolonged anorexia.
Fonti
- Mader's Reptile and Amphibian Medicine and Surgery, 3rd Edition, pages 315-321, 811-814.
- BSAVA Manual of Reptiles, 3rd Edition, pages 102-105, 210-212.
My highlights & notes
Segni e sintomi
Come si diagnostica
- RadiographyGold standard
- Plasma Biochemistry Panel
- Plasma Ionized Calcium
Approcci di trattamento
Il trattamento deve essere prescritto da un veterinario abilitato in base al vostro animale. Le dosi specifiche non sono mostrate di proposito.
Domande frequenti
What is Metabolic Bone Disease?
Metabolic Bone Disease (MBD), or nutritional secondary hyperparathyroidism, is a common and serious condition in captive reptiles and turtles. Caused by a lack of dietary calcium, improper calcium-to-phosphorus ratios, or insufficient UVB light, it leads to weak, deformed bones and muscle tremors. Learn how to recognize the signs, how veterinarians diagnose and treat it, and how proper husbandry can prevent this debilitating disease.
What are the symptoms of Metabolic Bone Disease?
Soft, deformed carapace or plastron、Soft, pliable mandible or maxilla (rubber jaw)、Loss of appetite、Lethargy and weakness、Muscle tremors or twitching、Pathological fractures、Swollen, firm limbs、Paresis or paralysis
How is Metabolic Bone Disease diagnosed?
Radiography、Plasma Biochemistry Panel、Plasma Ionized Calcium
How is Metabolic Bone Disease treated?
Il trattamento deve essere prescritto da un veterinario abilitato in base al vostro animale. Le dosi specifiche non sono mostrate di proposito.
Questo articolo è informativo e non sostituisce il parere veterinario. Se l’animale sta male, consultate un veterinario.
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