匹莫苯丹
別名: Vetmedin, Acardi, Cardisure, Pimocard, Fortekor-Plus
匹莫苯丹是一種幫助您的寵物心臟更有效泵血並擴張血管的藥物，從而減輕心臟的負擔。 * **給藥方式：** 請在**空腹**時給予此藥物，最好在餵食前一小時，以確保其被充分吸收。 * **嚴格的時間表：** 請盡量按照獸醫師的指示，精確地每隔 12 小時給藥一次。 * **終身治療：** 匹莫苯丹是控制心衰竭的治療方法，而非治癒方法。通常需要終身服用。未經獸醫師同意，**請勿自行停藥**。 * **居家監測：** 觀察寵物睡眠時的呼吸頻率（休息時呼吸頻率）。如果持續超過每分鐘 30 次，請聯繫您的獸醫師。 * **安全性：** 請放置於兒童和其他動物接觸不到的地方。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Management of myocardial failure (DCM), especially if not associated with taurine deficiency
- Heart failure associated with systolic dysfunction (Off-label)
- Management of the signs of mild, moderate or severe congestive heart failure due to AV valve insufficiency or dilated cardiomyopathy
- Treatment of congestive heart failure secondary to myxomatous mitral valve disease (MMVD)
- Treatment of heart failure secondary to dilated cardiomyopathy or chronic mitral valve insufficiency
- General dosing
- Adjunctive drug for the emergency treatment of CHF (if not overtly critical and a strong positive oral inotrope is needed)
- Adjunctive treatment of acute or chronic stage D heart failure (refractory to standard treatment)
- Congestive heart failure (MMVD or DCM) / Preclinical DCM / Preclinical MMVD
- Congestive heart failure (MMVD or DCM) / Preclinical DCM / Preclinical MMVD
給藥方式
可能的副作用
- Poor appetite
- Lethargy
- Diarrhea
- Dyspnea
- Azotemia
- Weakness and ataxia
- Pleural effusion
- Syncope
- Cough
- Ascites
- Heart murmur
- Arrhythmias (atrial fibrillation, increased ventricular ectopic beats)
- Worsening mitral valve lesions (acute hemorrhages, endocardial papilloform hyperplasia) with chronic use
- Moderate positive chronotropic effect (tachycardia)
- Vomiting (dose-dependent)
- Reduced appetite or lethargy (rare)
注意事項與禁忌
- Hypersensitivity to pimobendan
- Hypertrophic cardiomyopathy (HCM)
- Aortic stenosis
- Any condition where augmentation of cardiac output is inappropriate for functional or anatomic reasons
- Any condition where augmentation of cardiac output via increased contractility is not possible anatomically or functionally
- Use with caution in patients with **uncontrolled cardiac arrhythmias**. Safety has not been evaluated in: * Dogs younger than 6 months of age * Dogs with congenital heart defects * Dogs with diabetes mellitus or other serious metabolic diseases * Breeding, pregnant, or lactating animals (high doses in lab animals caused increased resorptions) > **Note:** Patients treated chronically should be regularly examined for worsening mitral valvular lesions and regurgitation.
藥物相互作用
- Verapamil: Calcium antagonist; attenuates pimobendan-induced increases in cardiac contractility.
- Propranolol: Beta-antagonist; attenuates pimobendan-induced increases in cardiac contractility.
- Diltiazem: Calcium channel blocker; assumed to potentially attenuate positive inotropic effects.
- Atenolol: Beta-blocker; assumed to potentially attenuate positive inotropic effects.
- Beta-blockers (e.g., atenolol, propranolol): Attenuates the positive inotropic effects of pimobendan
- Calcium-channel blockers (e.g., verapamil, diltiazem): Attenuates the positive inotropic effects of pimobendan
常見問題
匹莫苯丹用於寵物有什麼用途？
匹莫苯丹是一種幫助您的寵物心臟更有效泵血並擴張血管的藥物，從而減輕心臟的負擔。 • 給藥方式： 請在空腹時給予此藥物，最好在餵食前一小時，以確保其被充分吸收。 • 嚴格的時間表： 請盡量按照獸醫師的指示，精確地每隔 12 小時給藥一次。 • 終身治療： 匹莫苯丹是控制心衰竭的治療方法，而非治癒方法。通常需要終身服用。未經獸醫師同意，請勿自行停藥。 • 居家監測： 觀察寵物睡眠時的呼吸頻率（休息時呼吸頻率）。如果持續超過每分鐘 30 次，請聯繫您的獸醫師。 • 安全性： 請放置於兒童和其他動物接觸不到的地方。
匹莫苯丹對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。