奧比沙星
別名: Orbax, Posatex
藥物類別: Fluoroquinolone Antibiotic
- **給藥方式:** 請嚴格按照獸醫的指示給藥。即使您的寵物看起來已經好轉,也不要提早停藥,以防止產生抗藥性感染。 - **食物交互作用:** 請勿將此藥物與乳製品(如起司或牛奶)、制酸劑或含有鈣、鐵或鋅的補充劑同時餵食。這些物質會阻礙藥物吸收。請將這些食物與藥物間隔至少 2 小時。 - **副作用:** 最常見的副作用是嘔吐、腹瀉或食慾不振。如果這些症狀變得嚴重,請聯繫您的獸醫。 > **貓咪主人的重要注意事項:** 這種藥物極少數情況下會引起貓咪的視力問題。如果您發現貓咪的瞳孔異常放大或似乎有視力障礙,請立即停藥並聯繫您的獸醫。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Susceptible infections
- Skin infections (wounds and abscesses)
- Skin and other soft tissue infections
- Susceptible infections
- Susceptible infections
- Susceptible infections
- Urinary tract infections (cystitis) and skin/soft tissue infections (wounds and abscesses)
- Bacterial cystitis
- Skin and other soft tissue infections
- Otitis
給藥方式
POTopical
可能的副作用
- Anorexia
- Vomiting
- Diarrhea
- Arthropathies (cartilage damage) in immature, growing animals
- Potential retinal toxicity/blindness in cats (rare, but reported with higher doses of fluoroquinolones)
- CNS stimulation (rare)
- Cartilage abnormalities in growing animals
- CNS adverse effects (potentiated by NSAIDs)
- Retinal blindness in cats (dose-dependent)
注意事項與禁忌
- Immature dogs during the rapid growth phase (2-8 months in small/medium breeds; up to 18 months in large/giant breeds)
- Known hypersensitivity to orbifloxacin or other quinolones
- Giant-breed dogs <18 months old
- Large breeds <12 months old
- Small and medium-sized breeds <8 months old
- Pregnant or lactating bitches
- Animals intended for breeding
- Animals <4 months of age (otic preparation)
- Animals with a ruptured tympanum (otic preparation)
- Use with caution in animals with known or suspected CNS disorders (e.g., seizure disorders) as fluoroquinolones have rarely been associated with CNS stimulation. Safety in breeding or pregnant dogs and cats has not been established. Use higher dosages carefully in cats due to the potential risk of retinal toxicity.
藥物相互作用
- Antacids / Dairy Products: Cations (Mg++, Al+++, Ca++) bind to orbifloxacin and prevent its absorption; separate doses by at least 2 hours.
- Other Antibiotics (Aminoglycosides, 3rd-gen cephalosporins, extended-spectrum penicillins): Unpredictable synergism may occur against some bacteria (particularly Pseudomonas aeruginosa).
- Cyclosporine: May exacerbate nephrotoxicity and reduce the metabolism of systemic cyclosporine.
- Flunixin: May increase the AUC and elimination half-life of fluoroquinolones.
- Glyburide: Severe hypoglycemia is possible.
- Iron, Zinc (oral): Decreased orbifloxacin absorption; separate doses by at least 2 hours.
- Methotrexate: Increased methotrexate levels possible, resulting in toxicity.
- Nitrofurantoin: May antagonize the antimicrobial activity of fluoroquinolones; concomitant use is not recommended.
- Phenytoin: May alter phenytoin levels.
- Probenecid: Blocks tubular secretion, potentially increasing blood levels and half-life of orbifloxacin.
常見問題
奧比沙星用於寵物有什麼用途?
- **給藥方式:** 請嚴格按照獸醫的指示給藥。即使您的寵物看起來已經好轉,也不要提早停藥,以防止產生抗藥性感染。 - **食物交互作用:** 請勿將此藥物與乳製品(如起司或牛奶)、制酸劑或含有鈣、鐵或鋅的補充劑同時餵食。這些物質會阻礙藥物吸收。請將這些食物與藥物間隔至少 2 小時。 - **副作用:** 最常見的副作用是嘔吐、腹瀉或食慾不振。如果這些症狀變得嚴重,請聯繫您的獸醫。 > **貓咪主人的重要注意事項:** 這種藥物極少數情況下會引起貓咪的視力問題。如果您發現貓咪的瞳孔異常放大或似乎有視力障礙,請立即停藥並聯繫您的獸醫。
奧比沙星對我的寵物安全嗎?
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。