Tetracycline
別名: Aquadrops, Panmycin, Sumycin, Polyotic, Delta Albaplex
* **Administration**: Give this medication on an empty stomach if possible. Avoid giving within 1-2 hours of feeding, or giving milk/dairy products, as these can significantly decrease drug absorption. * **GI Upset**: If your pet vomits or acts nauseated, giving the medication with a small amount of non-dairy food may help, though it may reduce the drug's effectiveness slightly. * **Sunlight**: This medication may make your pet's skin more sensitive to sunlight (photosensitivity). Avoid prolonged sun exposure. * **Discoloration**: Be aware that in young, growing animals, this drug can cause permanent yellow or brown staining of the teeth.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Susceptible infections
- Soft tissue infections
- Hemotropic mycoplasmosis
- Bacteremia, systemic infections
- Rickettsial diseases
- Susceptible infections
- Susceptible infections
- Susceptible infections
- Susceptible infections in calves
- Susceptible infections in calves
- Susceptible infections
- Treatment of psittacosis
- Mild respiratory disease (flock treatment)
- Susceptible infections
給藥方式
可能的副作用
- Gastrointestinal distress (nausea, vomiting, anorexia, diarrhea)
- Discoloration of developing teeth and bones (yellow/brown/gray)
- Delayed bone growth and healing in young animals
- Superinfections (bacterial or fungal overgrowth)
- Photosensitivity
- Urolith formation (with long-term use in dogs)
- Hepatotoxicity and blood dyscrasias (rare)
- Cats: Colic, fever, hair loss, depression (poorly tolerated)
- Horses: Severe diarrhea (especially if stressed)
- Ruminants: Ruminal microflora depression and stasis (high oral doses)
- Injection site reactions (IM): Local necrosis and yellow staining
注意事項與禁忌
- Hypersensitivity to tetracyclines
- Pregnancy (last half) - retards fetal skeletal development and discolors teeth
- Young, growing animals (unless benefits outweigh risks)
- > **Extreme Caution**: Pregnancy (Category D). Can cause congenital malformations, embryotoxicity, and discoloration of deciduous teeth. * **Renal/Hepatic Impairment**: Use cautiously. Lower dosages and enhanced monitoring are recommended. Avoid concurrent nephrotoxic or hepatotoxic drugs. * **Cats**: Do not tolerate oral tetracycline well; monitor closely for adverse effects. * **IV Administration**: Rapid IV injection can cause transient collapse and cardiac arrhythmias due to calcium chelation. Administer slowly or pre-treat with IV calcium gluconate if rapid injection is necessary.
藥物相互作用
- Atovaquone: Tetracyclines may decrease atovaquone levels.
- Beta-lactam or Aminoglycoside Antibiotics: Theoretical antagonism of bactericidal activity, though clinical significance is doubtful.
- Digoxin: May increase bioavailability of digoxin, potentially causing toxicity that persists for months.
- Divalent or Trivalent Cations (Antacids, Calcium, Iron, Magnesium, Zinc, Bismuth): Chelation occurs, significantly decreasing the absorption of tetracycline. Separate doses by at least 1-2 hours.
- Methoxyflurane: Concomitant use can cause fatal nephrotoxicity.
- Sucralfate: May impair oral absorption of tetracycline; separate dosing by at least 2 hours.
- Warfarin: May depress plasma prothrombin activity; anticoagulant dosage adjustment may be needed.
常見問題
Tetracycline用於寵物有甚麼用途？
* **Administration**: Give this medication on an empty stomach if possible. Avoid giving within 1-2 hours of feeding, or giving milk/dairy products, as these can significantly decrease drug absorption. * **GI Upset**: If your pet vomits or acts nauseated, giving the medication with a small amount of non-dairy food may help, though it may reduce the drug's effectiveness slightly. * **Sunlight**: This medication may make your pet's skin more sensitive to sunlight (photosensitivity). Avoid prolonged sun exposure. * **Discoloration**: Be aware that in young, growing animals, this drug can cause permanent yellow or brown staining of the teeth.
Tetracycline對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。