Cholangitis
Cholangitis
Juga dikenali sebagai: Cholangiohepatitis, Neutrophilic cholangitis, Lymphocytic cholangitis, Suppurative cholangitis, Nonsuppurative cholangitis
Ringkasnya
Cholangitis is a common and treatable inflammatory disease of the liver and bile ducts, primarily affecting cats. Learn about its bacterial and immune-mediated forms, key symptoms like jaundice, and how veterinarians diagnose and treat this complex condition.
TL;DR. Kolangitis ialah keradangan salur hempedu yang lazim dan boleh dirawat; rawatan pantas mengawal jangkitan atau keradangan imun.
Pengesanan awal dan rawatan veterinar adalah penting.
Apa itu?
Keradangan salur hempedu. Jika melibatkan hati: kolangiohepatitis. Lebih lazim pada kucing. Bentuk: neutrofil (sering bakteria menaik) dan limfositik (sering imun, kronik). Pada kucing triaditis mungkin.
Hubungan rapat duktus hempedu dan pankreas.
Punca dan faktor risiko
Neutrofil: bakteria menaik (E. coli, Enterococcus, Streptococcus), sering dengan IBD/pankreatitis. Limfositik: imun dengan risiko fibrosis. Sejarah: Parsi dan Norwegian Forest; kini kucing tua tanpa predisposisi baka jelas.
"Cats with lymphocytic cholangitis were previously reported to be typically young to middle-aged, and Persians appeared to be overrepresented, but recent studies report it in older cats with no obvious breed predisposition (Callahan Clark et al, 2011; Warren et al, 2011)."
Tanda untuk dipantau
Lazim: ikterus, muntah, anoreksia, dehidrasi, susut berat, letargi.
Kadang-kadang: sakit abdomen, cirit-birit, asites, PU/PD, demam, hepatomegali.
Jarang: ptialisme, stupor, sawan (ensefalopati hepatik).
Ikterus ialah tanda lazim keradangan bilier lanjut.
Diagnosis
Biokimia, ultrasound abdomen, sitologi dan kultur hempedu, biopsi hati (standard emas).
Rawatan
Neutrofil: antibiotik 4–6 minggu ikut kultur, cth. amoxicillin/ampicillin, sering dengan metronidazole. Ursodiol dan SAMe. Limfositik: glukokortikoid selepas menolak jangkitan. Terapi bendalir.
Prognosis
Biasanya baik jika dirawat awal. Neutrofil: kerap sembuh. Limfositik: kronik, remisi mungkin.
Pencegahan
Tiada pencegahan pasti. Rawat penyakit GI awal dan pemeriksaan berkala.
Bila hubungi doktor haiwan
Kecemasan: ikterus, muntah berterusan, rebah, sawan, sakit abdomen teruk.
Baka
Parsi dan Norwegian Forest: risiko sejarah bentuk limfositik; kini mana-mana baka.
Sumber
- Small Animal Critical Care Medicine, 2nd Edition, page 679.
- Internal Medicine, 5th Edition, pages 577, 579, 580.
My highlights & notes
Tanda & simptom
Baka berisiko lebih tinggi
Cara didiagnosis
- Liver BiopsyStandard emas
- Abdominal Ultrasonography
- Bile culture
- Bile cytology
- Serum Biochemistry
Pendekatan rawatan
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Soalan lazim
What is Cholangitis?
Cholangitis is a common and treatable inflammatory disease of the liver and bile ducts, primarily affecting cats. Learn about its bacterial and immune-mediated forms, key symptoms like jaundice, and how veterinarians diagnose and treat this complex condition.
What are the symptoms of Cholangitis?
Loss of appetite、Dehydration、Yellowing of the skin and eyes (jaundice)、Lethargy、Vomiting (throwing up)、Weight loss (getting thinner)、Fluid in the belly (ascites)、Diarrhoea
How is Cholangitis diagnosed?
Liver Biopsy、Abdominal Ultrasonography、Bile culture、Bile cytology、Serum Biochemistry
How is Cholangitis treated?
Rawatan mesti dipreskripsikan doktor haiwan berlesen. Dos khusus sengaja tidak dipaparkan.
Sumber
- Internal Medicine 5th · p. 580
- Small Animal Critical Care Medicine, 2nd Edition (VetBooks.ir) · p. 679
- Internal Medicine 5th · p. 579
- Internal Medicine 5th · p. 577
- Internal Medicine 5th · p. 580
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