卡鉑
別名: Paraplatin
卡鉑是一種強效的化療藥物，用於治療您寵物的癌症。雖然通常耐受性良好，但您必須在家中遵守以下重要的安全和護理指引： * **排泄物處理：** 由於藥物及其活性代謝物會在治療後數天內隨尿液排出，**請避免直接接觸寵物的尿液、糞便和嘔吐物**。清理排泄物時請戴上拋棄式手套，並在事後徹底洗手。 * **「最低點（Nadir）」時期：** 卡鉑會暫時降低寵物的白血球數量，使其更容易受到感染。這個最低點通常發生在**狗治療後約14天**和**貓治療後約21天**。 * **何時聯繫獸醫：** 在最低點期間請密切觀察您的寵物。如果寵物出現**發燒、嚴重嗜睡、嘔吐或腹瀉**，請立即聯繫您的獸醫。 * **食慾與噁心：** 輸液後2至4天可能會出現輕微的噁心或食慾不振。您的獸醫可能會開立止吐藥物以保持寵物的舒適。 * **懷孕警告：** 孕婦、哺乳期婦女和免疫力低下的人應完全避免接觸寵物的排泄物。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Antineoplastic
- Neoplastic diseases (All uses)
- Neoplastic diseases (Intrapleural/intraperitoneal)
- Adenocarcinoma
- Antineoplastic
- Neoplastic diseases (All uses)
- Neoplastic diseases (Intrapleural/intraperitoneal)
- Equine sarcoids
- Antineoplastic
給藥方式
可能的副作用
- Bone marrow suppression (neutropenia, thrombocytopenia)
- Anorexia
- Vomiting (typically 2-4 days post-dose)
- Hepatotoxicity (elevated bilirubin and liver enzymes)
- Nephrotoxicity (less frequent than cisplatin)
- Neuropathies (rare)
- Ototoxicity (rare)
- Anaphylactoid reactions (rare)
- Hyperuricemia
注意事項與禁忌
- History of hypersensitivity to carboplatin or other platinum agents
- Severe bone marrow depression
- Pregnancy (fetotoxic and embryotoxic - Category D)
- **DO NOT give IM or SC.** Extreme caution is advised in patients with active infections, hearing impairment, or preexisting renal or hepatic disease. Patients with severe carboplatin-induced myelosuppression must recover their cell counts before additional therapy. **Equipment Warning:** Do not prepare, store, or administer using aluminum-containing needles or IV sets, as aluminum displaces platinum, causing a black precipitate and loss of potency.
藥物相互作用
- Aminoglycosides: Potential for increased risk of nephrotoxicity or ototoxicity.
- Cisplatin: Patients previously treated with cisplatin have an increased risk of developing neurotoxicity or ototoxicity after receiving carboplatin.
- Myelosuppressive drugs: The leukopenic or thrombocytopenic effects secondary to carboplatin may be enhanced.
- Radiation therapy: Potential for increased hematologic toxicity.
- Vaccines: Live or killed virus vaccines administered after therapy may have reduced efficacy. Carboplatin may also potentiate live virus vaccine replication and increase adverse effects.
- Nephrotoxic agents (e.g., NSAIDs, Amphotericin B): Increased risk of cumulative nephrotoxicity.
- Vaccines (live): May adversely affect the safety and efficacy of vaccinations due to immunosuppression.
- Radiotherapy: Potential to act as a radiosensitizer for patients receiving concomitant radiotherapy.
常見問題
卡鉑用於寵物有什麼用途？
卡鉑是一種強效的化療藥物，用於治療您寵物的癌症。雖然通常耐受性良好，但您必須在家中遵守以下重要的安全和護理指引： * **排泄物處理：** 由於藥物及其活性代謝物會在治療後數天內隨尿液排出，**請避免直接接觸寵物的尿液、糞便和嘔吐物**。清理排泄物時請戴上拋棄式手套，並在事後徹底洗手。 * **「最低點（Nadir）」時期：** 卡鉑會暫時降低寵物的白血球數量，使其更容易受到感染。這個最低點通常發生在**狗治療後約14天**和**貓治療後約21天**。 * **何時聯繫獸醫：** 在最低點期間請密切觀察您的寵物。如果寵物出現**發燒、嚴重嗜睡、嘔吐或腹瀉**，請立即聯繫您的獸醫。 * **食慾與噁心：** 輸液後2至4天可能會出現輕微的噁心或食慾不振。您的獸醫可能會開立止吐藥物以保持寵物的舒適。 * **懷孕警告：** 孕婦、哺乳期婦女和免疫力低下的人應完全避免接觸寵物的排泄物。
卡鉑對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。