Silymarin / Milk Thistle
別名: Marin, Denamarin, Legalon, Doxion, Hepaticare, Hepatosupport, Hepatosyl Plus, Samylin, Zentonil Advanced
> **What is Silymarin?** > Silymarin (Milk Thistle) is a natural nutritional supplement used to support and protect your pet's liver from damage, reduce inflammation, and promote liver healing. * **Administration:** Can be given with or without food. If your pet experiences stomach upset, try giving the supplement with a small meal or treat. * **Side Effects:** This supplement is generally very safe. It may occasionally cause mild diarrhea or vomiting. If these signs persist or become severe, contact your veterinarian. * **Patience is Key:** Because it is a supportive therapy, it may take several weeks of consistent use to see improvements in your pet's bloodwork or clinical condition. * **Quality Matters:** Since it is not an FDA-regulated drug, product quality varies. It is highly recommended to use the specific veterinary brand prescribed by your vet, as these are formulated for better absorption in pets.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Therapeutic dosage (general)
- Adjunctive therapy for chronic liver disease
- Chronic liver disease and ameliorating the effects of anticonvulsants
- Hepatotoxicity, hepatic recovery/regeneration, hepatic fibrosis
- General hepatic support
- Therapeutic dosage (general)
- Adjunctive therapy for chronic liver disease
- Chronic liver disease and ameliorating the effects of anticonvulsants
- Hepatotoxicity, hepatic recovery/regeneration, hepatic fibrosis
給藥方式
可能的副作用
- Gastrointestinal upset (mild nausea, vomiting, diarrhea)
- Allergic reactions in patients sensitive to the Asteraceae/Compositae plant family
- Generally very well tolerated
- Rare mild gastrointestinal upset
注意事項與禁忌
- Known hypersensitivity or allergy to the Asteraceae/Compositae plant family (ragweed, marigolds, daisies)
- Use caution with whole plant extracts (not the seed extract) in patients where exogenous estrogens are contraindicated, due to potential estrogen-like activity
- > **Important Warning:** Do not confuse Milk Thistle with Blessed Thistle, which is a completely different botanical compound. * **Regulatory Status:** These products are considered nutritional supplements and are not evaluated or approved by the FDA as pharmaceuticals. Potency and purity can vary between manufacturers. * **Pregnancy/Nursing:** Safety data during pregnancy or nursing is unavailable; weigh potential benefits against uncertain risks.
藥物相互作用
- CYP2C9 Substrates (e.g., warfarin, amitriptyline, verapamil): Silymarin may inhibit cytochrome P450 isoenzyme 2C9 (CYP2C9). Use caution with narrow therapeutic index drugs metabolized by this pathway.
- CYP3A4 Substrates: May inhibit CYP3A4, though clinical significance is currently undetermined.
- Drugs undergoing hepatic glucuronidation (acetaminophen, diazepam, morphine, lamotrigine): Silymarin may increase the clearance of these drugs (not applicable in cats). Clinical significance is undetermined.
常見問題
Silymarin / Milk Thistle用於寵物有甚麼用途？
> **What is Silymarin?** > Silymarin (Milk Thistle) is a natural nutritional supplement used to support and protect your pet's liver from damage, reduce inflammation, and promote liver healing. * **Administration:** Can be given with or without food. If your pet experiences stomach upset, try giving the supplement with a small meal or treat. * **Side Effects:** This supplement is generally very safe. It may occasionally cause mild diarrhea or vomiting. If these signs persist or become severe, contact your veterinarian. * **Patience is Key:** Because it is a supportive therapy, it may take several weeks of consistent use to see improvements in your pet's bloodwork or clinical condition. * **Quality Matters:** Since it is not an FDA-regulated drug, product quality varies. It is highly recommended to use the specific veterinary brand prescribed by your vet, as these are formulated for better absorption in pets.
Silymarin / Milk Thistle對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。