Amoxicillin/Clavulanate Potassium
別名: Clavamox, Augmentin, Amoclan
* **Administration:** You can give this medication with or without food. However, if your pet experiences stomach upset (vomiting or loss of appetite), giving the dose with a small meal or treat can help. * **Storage of Liquid:** If you are using the oral liquid suspension, it is best kept in the refrigerator. **Discard any unused liquid after 10 days**, as it loses its effectiveness. * **Completion of Therapy:** Always finish the entire prescription as directed by your veterinarian, even if your pet seems completely better. Stopping early can lead to resistant infections. * **Side Effects:** Mild diarrhea or vomiting can occur. Contact your veterinarian if these signs become severe or if your pet stops eating.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Susceptible infections
- Gram-positive infections
- Gram-negative infections
- Susceptible UTI's
- Susceptible skin, soft tissue infections
- Susceptible sepsis, pneumonia
- Susceptible infections
- Susceptible infections
- Susceptible infections (Ratites)
- Susceptible infections
- Susceptible UTI's
- Susceptible skin, soft tissue infections
- Susceptible deep pyodermas
- Systemic bacteremia
給藥方式
可能的副作用
- Gastrointestinal upset (anorexia, vomiting, diarrhea)
- Hypersensitivity reactions (rashes, fever, eosinophilia, anaphylaxis)
- Antibiotic-associated diarrhea and superinfections (due to altered gut flora)
- Neurotoxicity (e.g., ataxia in dogs) at very high doses or prolonged use
- Elevated liver enzymes (rare)
- Tachypnea, dyspnea, edema, and tachycardia (rarely reported in dogs)
注意事項與禁忌
- Patients with a history of hypersensitivity to penicillins
- Small hindgut fermenters (rabbits, guinea pigs, chinchillas, hamsters) due to risk of fatal clostridial enterotoxemia
- Oral administration in patients with septicemia, shock, or grave illness (due to delayed/diminished GI absorption)
- > **WARNING FOR EXOTIC PETS:** Do not administer penicillins to rabbits, guinea pigs, chinchillas, or hamsters, as severe enteritis and fatal clostridial enterotoxemia may occur. * **Cross-Reactivity:** Use cautiously in patients with documented hypersensitivity to other beta-lactam antibiotics (e.g., cephalosporins, carbapenems). * **Critically Ill Patients:** Avoid oral administration in patients in shock or with septicemia due to unreliable gastrointestinal absorption. * **Laboratory Interference:** May cause false-positive urine glucose determinations when using cupric sulfate solutions (e.g., Clinitest®).
藥物相互作用
- Bacteriostatic Antimicrobials (e.g., chloramphenicol, macrolides, tetracyclines, sulfonamides): Theoretical in vitro antagonism; clinical importance is currently in doubt but historically not recommended to combine.
- Methotrexate: Amoxicillin may decrease the renal excretion of methotrexate, causing increased levels and potential toxic effects.
- Probenecid: Competitively blocks the tubular secretion of most penicillins, thereby increasing serum levels and serum half-lives.
- Aminoglycosides: In vitro inactivation can occur if mixed together; serum concentrations of aminoglycosides may be falsely decreased if stored prior to analysis.
常見問題
Amoxicillin/Clavulanate Potassium用於寵物有甚麼用途？
* **Administration:** You can give this medication with or without food. However, if your pet experiences stomach upset (vomiting or loss of appetite), giving the dose with a small meal or treat can help. * **Storage of Liquid:** If you are using the oral liquid suspension, it is best kept in the refrigerator. **Discard any unused liquid after 10 days**, as it loses its effectiveness. * **Completion of Therapy:** Always finish the entire prescription as directed by your veterinarian, even if your pet seems completely better. Stopping early can lead to resistant infections. * **Side Effects:** Mild diarrhea or vomiting can occur. Contact your veterinarian if these signs become severe or if your pet stops eating.
Amoxicillin/Clavulanate Potassium對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。