カルプロフェン

使用用途

• Post-operative pain
• Analgesia
• Adjunct therapy for acute mastitis or respiratory disease
• Pain and Inflammation
• Analgesia
• Analgesia
• Osteoarthritis and Pain Management
• Analgesia

投与方法

考えられる副作用

• Vomiting
• Diarrhea
• Anorexia
• Lethargy
• Gastrointestinal ulceration or bleeding
• Hepatopathy (rare, idiosyncratic)
• Renal toxicity

注意事項と禁忌

• Bleeding disorders (e.g., Von Willebrand disease)
• Active gastrointestinal ulceration
• Hypersensitivity to carprofen or other NSAIDs
• Concurrent use with other NSAIDs or corticosteroids
• **Hepatotoxicity:** A rare, idiosyncratic (non-dose-dependent) hepatocellular toxicosis has been reported, primarily in dogs (notably Labrador Retrievers, though any breed can be affected). **Renal & GI:** Use with caution in dehydrated patients or those with pre-existing renal, hepatic, or cardiovascular disease. > **Warning:** Do not use concurrently with other NSAIDs or corticosteroids due to a significantly increased risk of severe gastrointestinal ulceration and perforation. Ensure a washout period (typically 5-7 days) when switching between NSAIDs.

薬物相互作用

• Corticosteroids: Significantly increased risk of gastrointestinal ulceration and perforation.
• Other NSAIDs: Increased risk of GI, renal, and hepatic toxicity.
• ACE Inhibitors: Potential for increased risk of renal toxicity and decreased hypotensive efficacy.
• Phenobarbital: Potential for altered metabolism and increased risk of hepatotoxicity.
• Furosemide: Decreased diuretic efficacy.

よくある質問