Amitraz
Also known as: Mitaban, Taktic, Preventic, ProMeris, Aludex, ProMeris (historical)
Amitraz is a potent medication used to treat severe mite infections. * **Safety First:** Always wear rubber gloves when applying the dip or handling the collar. Wash your hands thoroughly afterward. * **What to Expect:** Your pet may seem very sleepy or sluggish for 24 to 72 hours after a dip. This is a common side effect. Keep them warm and quiet. * **When to Call:** If your pet cannot be woken up, seems extremely cold, or if the sleepiness lasts more than 3 days, contact your veterinarian immediately. * **Warning:** Keep this product far away from cats and rabbits, as it can be fatal to them.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
What it is used for
- Generalized demodicosis (Labeled Protocol)
- Generalized demodicosis (Extra-label Protocol 1)
- Generalized demodicosis (Extra-label Protocol 2)
- Otic demodicosis
- Generalized mite infestations (canine demodicosis, sarcoptic acariasis and cheyletiellosis)
- Follicular demodicosis (Demodex cati)
- Surface demodicosis (Demodex gatoi)
- Mite treatment (Mice, Rats, Gerbils, Hamsters, Guinea pigs, Chinchillas)
How it is given
Possible side effects
- Transient sedation (up to 72 hours)
- Ataxia
- Bradycardia
- Vomiting and diarrhea
- Hypothermia
- Transient hyperglycemia
- Pruritus, erythema, and edema at application site
- Seizures (rare)
Cautions & contraindications
- Cats and rabbits (highly toxic, though extra-label protocols exist)
- Chihuahuas and toy breeds (use with extreme caution)
- Puppies less than 4 months of age
- Dogs with deep pyodermas and draining tracts (treat infection first)
- Brittle diabetic patients
- Pregnant or nursing animals
- > **Safety Warning:** Liquid concentrates are flammable until diluted. * Clients must wear rubber gloves when mixing and applying. * Wash hands and arms thoroughly after application. * Do not stress animals for at least 24 hours post-application. * Use ophthalmic protectants (e.g., petrolatum ointment) if treating near the eyes. * Dispose of unused diluted solution by flushing down the drain and do not reuse containers.
Drug interactions
- Corticosteroids: Immunosuppression can worsen demodicosis; concomitant use is contraindicated.
- Selegiline: Concurrent use of MAO inhibitors increases risk of toxicity.
- Amitriptyline: Concurrent use with tricyclic antidepressants is not recommended.
- Clomipramine: Concurrent use with tricyclic antidepressants is not recommended.
- Alpha-2 agonist sedatives (e.g., dexmedetomidine, xylazine): Additive or synergistic CNS depression and cardiovascular effects (bradycardia).
- Other ectoparasiticides: Potential for increased toxicity.
Frequently asked questions
What is Amitraz used for in pets?
Amitraz is a potent medication used to treat severe mite infections. * **Safety First:** Always wear rubber gloves when applying the dip or handling the collar. Wash your hands thoroughly afterward. * **What to Expect:** Your pet may seem very sleepy or sluggish for 24 to 72 hours after a dip. This is a common side effect. Keep them warm and quiet. * **When to Call:** If your pet cannot be woken up, seems extremely cold, or if the sleepiness lasts more than 3 days, contact your veterinarian immediately. * **Warning:** Keep this product far away from cats and rabbits, as it can be fatal to them.
Is Amitraz safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
This article is for general education and is not a substitute for professional veterinary advice. If your pet is unwell, please consult a veterinarian.
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