血管加壓素 / 抗利尿激素
別名: Pitressin, Neo-Lidocaton, Pressyn
### 寵物主人指引 * **僅限醫院使用**:血管加壓素是一種注射藥物,主要由獸醫師在醫院環境中使用。它用於診斷特定類型的過度飲水/排尿疾病(如尿崩症),或在嚴重休克或心搏驟停時作為救命的急救藥物。 * **診斷測試**:如果您的寵物正在進行「限水試驗」,牠們將在醫院接受密切監測。在測試結束時會給予血管加壓素,以觀察寵物的腎臟是否能對該荷爾蒙產生濃縮尿液的反應。 * **長期治療**:雖然過去曾在家中使用血管加壓素治療尿崩症,但現在已大多被一種更安全、更方便的合成滴劑或錠劑 **去氨加壓素 (DDAVP)** 所取代。 * **安全性**:因為它會強烈收縮血管,如果在緊急情況下使用,您的獸醫團隊將會密切監測寵物的心臟和血壓。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Diagnostic agent (after water deprivation test)
- Adjunctive treatment of vasodilatory shock (unresponsive to fluids/catecholamines)
- CPCR (pulseless electrical activity or ventricular asystole)
- Diagnostic agent (Exogenous vasopressin test after water deprivation test)
- Adjunctive treatment of vasodilatory shock (unresponsive to fluids/catecholamines)
- CPCR (pulseless electrical activity or ventricular asystole)
給藥方式
可能的副作用
- Local irritation at the injection site
- Sterile abscesses
- Skin reactions
- Platelet aggregation
- Bilirubinemia
- Abdominal pain
- Hematuria
- Hypersensitivity (urticarial) reactions
- Water intoxication (with overdosage)
注意事項與禁忌
- Known hypersensitivity to vasopressin
- Chronic nephritis until nitrogen retention is resolved to reasonable levels
- Cardiogenic shock (due to risk of myocardial ischemia)
- ### Important Warnings * **Cardiovascular Disease**: Use with extreme caution in patients with vascular disease or heart failure due to potent vasoconstrictive properties. High doses can cause myocardial ischemia. * **Other Conditions**: Use cautiously in patients with seizure disorders or asthma. * **Pregnancy**: FDA Category C. Has minimal effects on uterine contractions at usual doses, but should be used with caution in pregnant animals as animal studies have shown adverse fetal effects. * **Diagnostic Use**: The water deprivation test (WDT) is contraindicated in animals that are already dehydrated or have known renal disease.
藥物相互作用
- Alcohol: May inhibit the antidiuretic activity of vasopressin
- Demeclocycline: May inhibit the antidiuretic activity of vasopressin
- Epinephrine (large doses): May inhibit the antidiuretic activity of vasopressin
- Heparin: May inhibit the antidiuretic activity of vasopressin
- Norepinephrine (large doses): May inhibit the antidiuretic activity of vasopressin
- Antidepressants, Tricyclic: May potentiate the antidiuretic effects of vasopressin
- Carbamazepine: May potentiate the antidiuretic effects of vasopressin
- Chlorpropamide: May potentiate the antidiuretic effects of vasopressin
- Clofibrate: May potentiate the antidiuretic effects of vasopressin
- Fludrocortisone: May potentiate the antidiuretic effects of vasopressin
- Phenformin: May potentiate the antidiuretic effects of vasopressin
常見問題
血管加壓素 / 抗利尿激素用於寵物有什麼用途?
### 寵物主人指引 * **僅限醫院使用**:血管加壓素是一種注射藥物,主要由獸醫師在醫院環境中使用。它用於診斷特定類型的過度飲水/排尿疾病(如尿崩症),或在嚴重休克或心搏驟停時作為救命的急救藥物。 * **診斷測試**:如果您的寵物正在進行「限水試驗」,牠們將在醫院接受密切監測。在測試結束時會給予血管加壓素,以觀察寵物的腎臟是否能對該荷爾蒙產生濃縮尿液的反應。 * **長期治療**:雖然過去曾在家中使用血管加壓素治療尿崩症,但現在已大多被一種更安全、更方便的合成滴劑或錠劑 **去氨加壓素 (DDAVP)** 所取代。 * **安全性**:因為它會強烈收縮血管,如果在緊急情況下使用,您的獸醫團隊將會密切監測寵物的心臟和血壓。
血管加壓素 / 抗利尿激素對我的寵物安全嗎?
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育,不能取代專業獸醫意見。如寵物身體不適,請諮詢獸醫。