Vasopressin
別名: Pitressin, Neo-Lidocaton, Pressyn
### Information for Pet Owners * **Hospital Use Only**: Vasopressin is an injectable medication primarily used by veterinarians in a hospital setting. It is used either to diagnose specific types of excessive drinking/urination disorders (like Diabetes Insipidus) or as a life-saving emergency drug during severe shock or cardiac arrest. * **Diagnostic Testing**: If your pet is undergoing a "water deprivation test," they will be closely monitored in the hospital. Vasopressin is given at the end of the test to see if your pet's kidneys can concentrate urine in response to the hormone. * **Long-term Treatment**: While vasopressin was historically used to treat Diabetes Insipidus at home, it has largely been replaced by a safer, more convenient synthetic drop or tablet called **desmopressin (DDAVP)**. * **Safety**: Because it strongly constricts blood vessels, your veterinary team will monitor your pet's heart and blood pressure closely if it is used in an emergency.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Diagnostic agent (after water deprivation test)
- Adjunctive treatment of vasodilatory shock (unresponsive to fluids/catecholamines)
- CPCR (pulseless electrical activity or ventricular asystole)
- Diagnostic agent (Exogenous vasopressin test after water deprivation test)
- Adjunctive treatment of vasodilatory shock (unresponsive to fluids/catecholamines)
- CPCR (pulseless electrical activity or ventricular asystole)
給藥方式
可能的副作用
- Local irritation at the injection site
- Sterile abscesses
- Skin reactions
- Platelet aggregation
- Bilirubinemia
- Abdominal pain
- Hematuria
- Hypersensitivity (urticarial) reactions
- Water intoxication (with overdosage)
注意事項與禁忌
- Known hypersensitivity to vasopressin
- Chronic nephritis until nitrogen retention is resolved to reasonable levels
- Cardiogenic shock (due to risk of myocardial ischemia)
- ### Important Warnings * **Cardiovascular Disease**: Use with extreme caution in patients with vascular disease or heart failure due to potent vasoconstrictive properties. High doses can cause myocardial ischemia. * **Other Conditions**: Use cautiously in patients with seizure disorders or asthma. * **Pregnancy**: FDA Category C. Has minimal effects on uterine contractions at usual doses, but should be used with caution in pregnant animals as animal studies have shown adverse fetal effects. * **Diagnostic Use**: The water deprivation test (WDT) is contraindicated in animals that are already dehydrated or have known renal disease.
藥物相互作用
- Alcohol: May inhibit the antidiuretic activity of vasopressin
- Demeclocycline: May inhibit the antidiuretic activity of vasopressin
- Epinephrine (large doses): May inhibit the antidiuretic activity of vasopressin
- Heparin: May inhibit the antidiuretic activity of vasopressin
- Norepinephrine (large doses): May inhibit the antidiuretic activity of vasopressin
- Antidepressants, Tricyclic: May potentiate the antidiuretic effects of vasopressin
- Carbamazepine: May potentiate the antidiuretic effects of vasopressin
- Chlorpropamide: May potentiate the antidiuretic effects of vasopressin
- Clofibrate: May potentiate the antidiuretic effects of vasopressin
- Fludrocortisone: May potentiate the antidiuretic effects of vasopressin
- Phenformin: May potentiate the antidiuretic effects of vasopressin
常見問題
Vasopressin用於寵物有甚麼用途？
### Information for Pet Owners * **Hospital Use Only**: Vasopressin is an injectable medication primarily used by veterinarians in a hospital setting. It is used either to diagnose specific types of excessive drinking/urination disorders (like Diabetes Insipidus) or as a life-saving emergency drug during severe shock or cardiac arrest. * **Diagnostic Testing**: If your pet is undergoing a "water deprivation test," they will be closely monitored in the hospital. Vasopressin is given at the end of the test to see if your pet's kidneys can concentrate urine in response to the hormone. * **Long-term Treatment**: While vasopressin was historically used to treat Diabetes Insipidus at home, it has largely been replaced by a safer, more convenient synthetic drop or tablet called **desmopressin (DDAVP)**. * **Safety**: Because it strongly constricts blood vessels, your veterinary team will monitor your pet's heart and blood pressure closely if it is used in an emergency.
Vasopressin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。