柳氮磺吡啶 / 磺胺沙拉嗪
別名: Azulfidine, Azulfidine EN-tabs, Salazopyrin
藥物類別: Antibacterial / Anti-inflammatory / Immunosuppressive (Sulfonamide/Salicylate)
> **重要警告**：此藥物可能導致狗出現「乾眼症」（角膜結膜炎），若忽視可能導致永久性失明。 - **密切觀察寵物的眼睛**。如果您發現寵物瞇眼、眼睛發紅、出現濃稠的黃綠色眼屎，或眼睛看起來混濁乾燥，請立即聯繫您的獸醫師。 - **給藥方式**：請與食物一起餵食以減少腸胃不適。如果使用的是腸溶錠，請勿壓碎或剝半。 - **貓咪注意事項**：貓對此藥物非常敏感。請嚴格遵守獸醫師的劑量指示，且勿超過處方的治療天數。 - **副作用**：注意是否出現食慾不振、嘔吐或牙齦/眼睛發黃（黃疸）的現象。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- All uses (Management of colitis)
- General
- General
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- Chronic colitis
- Inflammatory large bowel disease
- Adjunctive treatment of vasculitis
- Adjunctive treatment of vasculitis
- All uses (Management of colitis)
給藥方式
PO
可能的副作用
- Keratoconjunctivitis sicca (KCS) in dogs
- Anorexia
- Vomiting
- Cholestatic jaundice
- Hemolytic anemia
- Leukopenia
- Decreased sperm counts
- Allergic dermatitis
- Keratoconjunctivitis sicca (KCS)
注意事項與禁忌
- Hypersensitivity to sulfasalazine, sulfonamides, or salicylates
- Intestinal or urinary obstructions
- Doberman pinschers (highly susceptible to sulfonamide-induced polysystemic immune complex disease)
- Dobermanns (appear to be highly sensitive to adverse effects associated with sulfapyridine)
- Patients with known hypersensitivity to sulfonamides or salicylates
- Use with caution in animals with preexisting **liver, renal, or hematologic diseases**. > **Feline Warning**: Because cats have a deficient glucuronidation pathway, they are highly sensitive to salicylates. Use extreme caution and strict dosing when using this drug in cats. Use with caution in nursing patients, as sulfonamides are excreted in milk and may cause kernicterus in newborns.
藥物相互作用
- Chlorpropamide: Hypoglycemic effects could be potentiated
- Digoxin: Sulfasalazine may reduce absorption of digoxin
- Ferrous sulfate (or other iron salts): May decrease the blood levels of sulfasalazine if administered concurrently
- Folic acid: Oral absorption of folic acid may be inhibited
- Warfarin: Potentially sulfasalazine could potentiate warfarin
- Folate: Measurement of serum folate concentration may be affected
- Thyroxine: May cause a reduction in serum thyroxine concentrations
常見問題
柳氮磺吡啶 / 磺胺沙拉嗪用於寵物有什麼用途？
> **重要警告**：此藥物可能導致狗出現「乾眼症」（角膜結膜炎），若忽視可能導致永久性失明。 - **密切觀察寵物的眼睛**。如果您發現寵物瞇眼、眼睛發紅、出現濃稠的黃綠色眼屎，或眼睛看起來混濁乾燥，請立即聯繫您的獸醫師。 - **給藥方式**：請與食物一起餵食以減少腸胃不適。如果使用的是腸溶錠，請勿壓碎或剝半。 - **貓咪注意事項**：貓對此藥物非常敏感。請嚴格遵守獸醫師的劑量指示，且勿超過處方的治療天數。 - **副作用**：注意是否出現食慾不振、嘔吐或牙齦/眼睛發黃（黃疸）的現象。
柳氮磺吡啶 / 磺胺沙拉嗪對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。