Sulfasalazine
別名: Azulfidine, Azulfidine EN-tabs, Salazopyrin
> **CRITICAL WARNING**: This medication can cause "dry eye" (Keratoconjunctivitis sicca) in dogs, which can lead to permanent blindness if ignored. - **Monitor your pet's eyes closely**. Contact your veterinarian immediately if you notice squinting, redness, thick yellow/green eye discharge, or if the eyes appear dull and dry. - **Administration**: Give with food to reduce stomach upset. If using enteric-coated tablets, do not crush or break them. - **Cats**: Cats are highly sensitive to this medication. Follow your veterinarian's exact dosing instructions and do not exceed the prescribed duration. - **Side Effects**: Watch for loss of appetite, vomiting, or yellowing of the gums/eyes (jaundice).
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- All uses (Management of colitis)
- General
- General
- Inflammatory large bowel disease
- Inflammatory large bowel disease
- Chronic colitis
- Inflammatory large bowel disease
- Adjunctive treatment of vasculitis
- Adjunctive treatment of vasculitis
- All uses (Management of colitis)
給藥方式
可能的副作用
- Keratoconjunctivitis sicca (KCS) in dogs
- Anorexia
- Vomiting
- Cholestatic jaundice
- Hemolytic anemia
- Leukopenia
- Decreased sperm counts
- Allergic dermatitis
- Keratoconjunctivitis sicca (KCS)
注意事項與禁忌
- Hypersensitivity to sulfasalazine, sulfonamides, or salicylates
- Intestinal or urinary obstructions
- Doberman pinschers (highly susceptible to sulfonamide-induced polysystemic immune complex disease)
- Dobermanns (appear to be highly sensitive to adverse effects associated with sulfapyridine)
- Patients with known hypersensitivity to sulfonamides or salicylates
- Use with caution in animals with preexisting **liver, renal, or hematologic diseases**. > **Feline Warning**: Because cats have a deficient glucuronidation pathway, they are highly sensitive to salicylates. Use extreme caution and strict dosing when using this drug in cats. Use with caution in nursing patients, as sulfonamides are excreted in milk and may cause kernicterus in newborns.
藥物相互作用
- Chlorpropamide: Hypoglycemic effects could be potentiated
- Digoxin: Sulfasalazine may reduce absorption of digoxin
- Ferrous sulfate (or other iron salts): May decrease the blood levels of sulfasalazine if administered concurrently
- Folic acid: Oral absorption of folic acid may be inhibited
- Warfarin: Potentially sulfasalazine could potentiate warfarin
- Folate: Measurement of serum folate concentration may be affected
- Thyroxine: May cause a reduction in serum thyroxine concentrations
常見問題
Sulfasalazine用於寵物有甚麼用途？
> **CRITICAL WARNING**: This medication can cause "dry eye" (Keratoconjunctivitis sicca) in dogs, which can lead to permanent blindness if ignored. - **Monitor your pet's eyes closely**. Contact your veterinarian immediately if you notice squinting, redness, thick yellow/green eye discharge, or if the eyes appear dull and dry. - **Administration**: Give with food to reduce stomach upset. If using enteric-coated tablets, do not crush or break them. - **Cats**: Cats are highly sensitive to this medication. Follow your veterinarian's exact dosing instructions and do not exceed the prescribed duration. - **Side Effects**: Watch for loss of appetite, vomiting, or yellowing of the gums/eyes (jaundice).
Sulfasalazine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。