설파살라진

용도

• Inflammatory large bowel disease
• Inflammatory large bowel disease
• Inflammatory large bowel disease
• Inflammatory large bowel disease
• All uses (Management of colitis)
• General
• General
• Inflammatory large bowel disease
• Inflammatory large bowel disease
• Chronic colitis
• Inflammatory large bowel disease
• Adjunctive treatment of vasculitis
• Adjunctive treatment of vasculitis
• All uses (Management of colitis)

투여 방법

가능한 부작용

• Keratoconjunctivitis sicca (KCS) in dogs
• Anorexia
• Vomiting
• Cholestatic jaundice
• Hemolytic anemia
• Leukopenia
• Decreased sperm counts
• Allergic dermatitis
• Keratoconjunctivitis sicca (KCS)

주의사항 및 금기

• Hypersensitivity to sulfasalazine, sulfonamides, or salicylates
• Intestinal or urinary obstructions
• Doberman pinschers (highly susceptible to sulfonamide-induced polysystemic immune complex disease)
• Dobermanns (appear to be highly sensitive to adverse effects associated with sulfapyridine)
• Patients with known hypersensitivity to sulfonamides or salicylates
• Use with caution in animals with preexisting **liver, renal, or hematologic diseases**. > **Feline Warning**: Because cats have a deficient glucuronidation pathway, they are highly sensitive to salicylates. Use extreme caution and strict dosing when using this drug in cats. Use with caution in nursing patients, as sulfonamides are excreted in milk and may cause kernicterus in newborns.

약물 상호작용

• Chlorpropamide: Hypoglycemic effects could be potentiated
• Digoxin: Sulfasalazine may reduce absorption of digoxin
• Ferrous sulfate (or other iron salts): May decrease the blood levels of sulfasalazine if administered concurrently
• Folic acid: Oral absorption of folic acid may be inhibited
• Warfarin: Potentially sulfasalazine could potentiate warfarin
• Folate: Measurement of serum folate concentration may be affected
• Thyroxine: May cause a reduction in serum thyroxine concentrations

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