索他洛爾
別名: Betapace, Sotacor
藥物類別: Beta-Adrenergic Blocker / Class III Antiarrhythmic
> **重要提示**：未經獸醫師同意，請勿突然停藥或更改劑量。突然停藥可能會導致危險的心律不整反彈或血壓升高。 * **給藥方式**：為了獲得最佳吸收效果，如果您的寵物能適應，建議空腹給藥。如果引起腸胃不適，可以與少量食物一起餵食。 * **觀察與監測**：密切觀察您的寵物是否出現極度疲倦、虛弱、昏厥或呼吸困難的跡象。 * **溝通**：如果發現寵物有嘔吐、嗜睡或呼吸問題，請立即聯繫您的獸醫師。請務必按時回診進行心電圖 (ECG) 監測，以確保藥物安全有效。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- General antiarrhythmic
- For ventricular tachyarrhythmias
- General antiarrhythmic
- General antiarrhythmic
- Ventricular arrhythmias
- General antiarrhythmic
- General antiarrhythmic
- For ventricular tachycardia
- For ventricular tachyarrhythmias in Boxers in combination with mexiletine
- In Boxers
- Ventricular arrhythmias
- Ventricular arrhythmias (Acute/Severe)
給藥方式
POIV
可能的副作用
- Negative inotropism (decreased heart contractility)
- Proarrhythmia (can induce new or worsen existing arrhythmias)
- Dyspnea / Bronchospasm
- Fatigue / Lethargy
- Dizziness / Syncope exacerbation
- Nausea / Vomiting
- Bradycardia
- Hypotension
- Bradyarrhythmias
- Bronchospasm
- Depression
- Nausea
- Vomiting
- Diarrhoea
注意事項與禁忌
- Asthma or reactive airway disease
- Sinus bradycardia
- 2nd or 3rd degree AV block (unless artificially paced)
- Long QT syndromes
- Cardiogenic shock
- Uncontrolled congestive heart failure (CHF)
- Asthma
- Atrioventricular (AV) block
- Decompensated congestive heart failure (CHF)
- Long QT interval on ECG
- Use with caution in patients with congestive heart failure (due to negative inotropic effects), diabetes mellitus, or hyperthyroidism (may mask clinical signs of hypoglycemia or thyrotoxicosis). Use with caution in patients with renal dysfunction; dosage intervals may need to be extended as it is renally excreted. Safety in pregnancy is not fully established (FDA Category B). Sotalol enters maternal milk at up to 5x serum concentrations; consider milk replacer for nursing animals.
藥物相互作用
- Amiodarone: May prolong refractory periods; concurrent use not recommended.
- Anesthetics, General: Additive myocardial depression may occur.
- Antacids: May reduce oral sotalol absorption; separate doses by at least 2 hours.
- Antiarrhythmics, Class IA (quinidine, procainamide, disopyramide): May prolong refractory periods and QT interval; concurrent use not recommended.
- Antiarrhythmics, Class IB/IC (lidocaine, mexiletine, phenytoin, flecainide): May prolong QT interval.
- Calcium Channel Blockers (verapamil, diltiazem): Potential to increase hypotensive effects; additive effects on AV conduction or ventricular function. Use with caution.
- Cisapride: May prolong QT interval.
- Clonidine: Increased risk for rebound hypertension if clonidine is discontinued after concomitant therapy.
- Digoxin: Potential for increased risks for proarrhythmic events.
- Erythromycin / Clarithromycin: May prolong QT interval.
- Lidocaine: Clearance of lidocaine may be impaired by sotalol.
常見問題
索他洛爾用於寵物有什麼用途？
> **重要提示**：未經獸醫師同意，請勿突然停藥或更改劑量。突然停藥可能會導致危險的心律不整反彈或血壓升高。 * **給藥方式**：為了獲得最佳吸收效果，如果您的寵物能適應，建議空腹給藥。如果引起腸胃不適，可以與少量食物一起餵食。 * **觀察與監測**：密切觀察您的寵物是否出現極度疲倦、虛弱、昏厥或呼吸困難的跡象。 * **溝通**：如果發現寵物有嘔吐、嗜睡或呼吸問題，請立即聯繫您的獸醫師。請務必按時回診進行心電圖 (ECG) 監測，以確保藥物安全有效。
索他洛爾對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。