維生素C / 抗壞血酸

用途

給藥方式

可能的副作用

• Gastrointestinal upset (diarrhea) with high oral doses
• Pain or tissue irritation at the injection site (IM or SC)
• Increased risk of calcium oxalate urolithiasis with chronic high-dose administration
• Gastrointestinal upset (diarrhea) at high oral doses
• Pain at injection site (IM/SC)
• Potential to acidify urine, which may increase the risk of oxalate or urate urolithiasis

注意事項與禁忌

• Patients with a history of urate or calcium oxalate urolithiasis
• Use with caution in patients with iron storage diseases (e.g., hemochromatosis)
• Patients with a history of calcium oxalate or urate urolithiasis (due to urine acidification)
• Use with extreme caution in animals prone to **calcium oxalate urolithiasis**, as ascorbic acid is partially metabolized to oxalate and excreted in the urine. Intravenous administration should be performed slowly to avoid adverse cardiovascular events. Injectable solutions should be protected from light.

藥物相互作用

• Deferoxamine: Concurrent use may exacerbate tissue iron toxicity, particularly in the heart.
• Urine acidifying agents: May have additive acidifying effects, potentially increasing the risk of crystalluria.

常見問題