雷尼替丁
別名: Zantac, Zantac 75, Zantac EFFERdose
**雷尼替丁 (Ranitidine)** 是一種用於減少胃酸並幫助食物更順暢地通過消化道的藥物。 * **給藥方式：** 請務必完全依照獸醫師的指示給藥。請勿漏掉劑量，否則胃酸濃度可能會反彈，導致症狀復發。 * **給藥時間：** 可以與食物一起或空腹給予。如果您的寵物同時服用制酸劑（胃藥），請與雷尼替丁間隔至少 2 小時。 * **副作用：** 雷尼替丁通常非常安全且耐受性良好。副作用很少見，但可能包括輕微的腸胃不適。 * **保存方式：** 請將藥錠保存在密封容器中，置於室溫下並避免陽光直射。 > **注意：** 在給予任何新藥物或保健品之前，請務必諮詢您的獸醫師，儘管雷尼替丁的藥物交互作用比舊款制酸劑（如西咪替丁）來得少。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- For ulcer disease/esophagitis
- For ulcer disease/esophagitis
- For ulcer disease/esophagitis
- As a prokinetic agent to stimulate colonic motility
- As a prokinetic agent to stimulate colonic motility
- All uses
- All uses
- For Helicobacter mustelae
- Foals
- Foals
- Adults
- As a prokinetic in rabbits
- For suspected gastric ulceration in rabbits
- For esophagitis
- For chronic gastritis
- For ulcer disease
- For ulcer disease
- For ulcer disease (also used for esophagitis)
- For ulcer disease
- For gastrinoma
- For gastrinoma
- To treat hypergastrinemia secondary to chronic renal failure
- To treat hyperhistaminemia secondary to mast cell tumors
- As a prokinetic agent to stimulate gastric contractions
- All uses (ulcers, gastritis, prokinetic)
給藥方式
可能的副作用
- Vomiting (associated with rapid IV boluses in small animals)
- Pain at the injection site (IM administration)
- Mental confusion (rare, documented in humans)
- Headache (rare, documented in humans)
- Agranulocytosis (rare)
- Transient cardiac arrhythmias (if given too rapidly IV)
- Cardiac arrhythmias (rare, typically with rapid IV)
- Hypotension (rare, typically with rapid IV)
注意事項與禁忌
- Hypersensitivity to ranitidine
- No specific contraindications available in the monograph
- Use cautiously and consider reduced dosages in patients with **diminished renal function** or **hepatic insufficiency**, as the drug may accumulate. **Geriatric patients** may be more susceptible to adverse effects. High-dose, chronic IV therapy (longer than 5 days) has caused increased serum ALT levels in humans; monitoring liver enzymes is recommended in these scenarios. Use with caution in nursing veterinary patients, as ranitidine is excreted in breast milk (milk:plasma ratio of 5:1 to 12:1).
藥物相互作用
- Acetaminophen: Ranitidine (dose-dependent) may inhibit acetaminophen metabolism.
- Antacids: High doses may decrease the absorption of ranitidine; administer at least 2 hours apart.
- Ketoconazole: Absorption of ketoconazole may be reduced secondary to increased gastric pH.
- Itraconazole: Absorption of itraconazole may be reduced secondary to increased gastric pH.
- Metoprolol: Ranitidine may increase metoprolol half-life and peak serum levels.
- Nifedipine: Ranitidine may increase nifedipine AUC by 30%.
- Propantheline: Delays the absorption but increases the peak serum level of ranitidine; relative bioavailability may be increased by 23%.
- Vitamin B-12: Long-term ranitidine use may reduce oral absorption of Vitamin B-12.
- Sucralfate: May affect absorption; advisable to administer sucralfate 2 hours before H2 blockers
- Digoxin: Ranitidine may reduce absorption or effect; stagger oral doses by 2 hours
- Metoclopramide: Ranitidine may reduce absorption or effect; stagger oral doses by 2 hours
常見問題
雷尼替丁用於寵物有甚麼用途？
雷尼替丁 (Ranitidine) 是一種用於減少胃酸並幫助食物更順暢地通過消化道的藥物。 • 給藥方式： 請務必完全依照獸醫師的指示給藥。請勿漏掉劑量，否則胃酸濃度可能會反彈，導致症狀復發。 • 給藥時間： 可以與食物一起或空腹給予。如果您的寵物同時服用制酸劑（胃藥），請與雷尼替丁間隔至少 2 小時。 • 副作用： 雷尼替丁通常非常安全且耐受性良好。副作用很少見，但可能包括輕微的腸胃不適。 • 保存方式： 請將藥錠保存在密封容器中，置於室溫下並避免陽光直射。 > 注意： 在給予任何新藥物或保健品之前，請務必諮詢您的獸醫師，儘管雷尼替丁的藥物交互作用比舊款制酸劑（如西咪替丁）來得少。
雷尼替丁對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。