Ivermectin
別名: Heartgard, Ivomec, Equimectrin, Eqvalan, Zimectrin, Equimax, Phoenectin, Tri-Heart Plus, Panacur Plus, Stromectol, Otimectin Vet, Panomec
### Important Information for Pet Owners * **Heartworm Prevention:** When used at the prescribed low doses for heartworm prevention, ivermectin is extremely safe for all breeds of dogs and cats. * **Breed Sensitivities:** Certain herding breeds (like Collies, Australian Shepherds, and Shetland Sheepdogs) can have a genetic mutation that makes them highly sensitive to ivermectin at higher doses. Your veterinarian may recommend a genetic test before using this drug for conditions like mange. * **Signs of Toxicity:** Contact your veterinarian immediately if your pet shows signs of stumbling, dilated pupils, drooling, tremors, lethargy, or blindness after receiving this medication. * **Handling Precautions:** If using large animal liquid or paste products, wash your hands after use and avoid contact with your eyes. Do not eat or smoke while handling. * **Environmental Safety:** Dispose of unused products carefully. Ivermectin is highly toxic to fish and water-borne organisms; do not dispose of it in lakes, streams, or ponds.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- As a preventative for heartworm
- For Aelurostrongylus abstrusus
- Ear mites
- For susceptible parasites
- For general control of endo- and ectoparasites in potbellied pigs
- For prevention of heartworm disease
- To treat heartworm disease using the very slow protocol
- For nasal bot infection
- For susceptible parasites
- For adjunctive treatment of meningeal worm (Parelaphostrongylus tenuis)
- Camelids: For susceptible parasites
- Camelids: For GI helminths
- Camelids: For adjunctive treatment of meningeal worm
給藥方式
可能的副作用
- Horses: Ventral midline swelling and pruritus (hypersensitivity to dying Onchocerca microfilariae)
- Dogs: Shock-like reaction (when used as microfilaricide), depression, hypothermia, vomiting
- Dogs (MDR1/Toxicity): Ataxia, lethargy, hypersalivation, mydriasis, tremors, seizures, blindness, coma
- Cats: Agitation, vocalization, anorexia, mydriasis, rear limb paresis, tremors, disorientation, blindness
- Cattle: Paralysis/staggering or salivation/bloat (if Hypoderma bovis larvae are killed in vital areas), injection site swelling
- Birds: Lethargy, anorexia, death (especially in finches and budgerigars)
- Neurotoxicity (ataxia, tremors, mydriasis, blindness, coma, death) - especially in MDR1-mutant dogs
- Hypersalivation
- Vomiting
- Lethargy
- Bradycardia
注意事項與禁忌
- Foals less than 4 months old (manufacturer recommendation)
- Puppies less than 6 weeks old
- Breeds susceptible to ABCB1-1Δ (MDR1) mutation at high doses (unless tested normal)
- Chelonians (turtles, tortoises)
- Indigo snakes
- Skinks
- Lactating dairy animals (no milk withdrawal established)
- Females of breeding age (cattle/swine, per label)
- Dogs with the MDR1 (ABCB1) gene mutation (unless using strictly at low heartworm preventative doses)
- Chelonians (turtles and tortoises) - causes fatal flaccid paralysis
- Kittens under 16 weeks of age (for topical ear gel)
- Use of concentrated livestock formulations in small animals
藥物相互作用
- Benzodiazepines: Effects may be potentiated by ivermectin; concurrent use is not advised.
- Ketamine: Avoid ivermectin in reptiles within 10 days of ketamine administration.
- Spinosad: Increased risk of neurotoxicity; do not use with high extra-label doses of ivermectin.
- Amiodarone: P-glycoprotein inhibitor; increases risk of ivermectin CNS toxicity.
- Carvedilol: P-glycoprotein inhibitor; increases risk of ivermectin CNS toxicity.
- Clarithromycin: P-glycoprotein inhibitor; increases risk of ivermectin CNS toxicity.
- Cyclosporine: P-glycoprotein inhibitor; increases risk of ivermectin CNS toxicity.
- Diltiazem: P-glycoprotein inhibitor; increases risk of ivermectin CNS toxicity.
- Erythromycin: P-glycoprotein inhibitor; increases risk of ivermectin CNS toxicity.
- Itraconazole: P-glycoprotein inhibitor; increases risk of ivermectin CNS toxicity.
- Ketoconazole: Strong P-glycoprotein inhibitor; should never be used with ivermectin in dogs.
常見問題
Ivermectin用於寵物有甚麼用途？
### Important Information for Pet Owners * **Heartworm Prevention:** When used at the prescribed low doses for heartworm prevention, ivermectin is extremely safe for all breeds of dogs and cats. * **Breed Sensitivities:** Certain herding breeds (like Collies, Australian Shepherds, and Shetland Sheepdogs) can have a genetic mutation that makes them highly sensitive to ivermectin at higher doses. Your veterinarian may recommend a genetic test before using this drug for conditions like mange. * **Signs of Toxicity:** Contact your veterinarian immediately if your pet shows signs of stumbling, dilated pupils, drooling, tremors, lethargy, or blindness after receiving this medication. * **Handling Precautions:** If using large animal liquid or paste products, wash your hands after use and avoid contact with your eyes. Do not eat or smoke while handling. * **Environmental Safety:** Dispose of unused products carefully. Ivermectin is highly toxic to fish and water-borne organisms; do not dispose of it in lakes, streams, or ponds.
Ivermectin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。