Dopamine
別名: Intropin
Dopamine is a critical care medication used exclusively in a hospital setting, typically in an Intensive Care Unit (ICU). * **Purpose**: It is used to support your pet's blood pressure, heart function, and organ blood flow during life-threatening conditions like severe shock or heart failure. * **Administration**: It is given as a continuous intravenous (IV) drip using a specialized pump to ensure exact dosing. * **Monitoring**: While on this medication, your pet will be closely monitored by the veterinary team, including continuous heart rate, ECG, and blood pressure checks. * **Safety**: The veterinary team will frequently check the IV catheter, as this medication can cause tissue damage if it leaks outside the vein.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Vasodilatory shock if fluid resuscitation and dobutamine is not successful
- Treatment of severe hypotension/shock
- Treatment of severe hypotension/shock after fluid correction and if dobutamine does not give desired effect
- Vasodilatory shock if fluid resuscitation and dobutamine is not successful
- Adjunctive therapy for acute heart failure
- Treatment of severe hypotension/shock
- Treatment of severe hypotension/shock after fluid correction and if dobutamine does not give desired effect
- Adjunctive therapy for oliguric renal failure
給藥方式
可能的副作用
- Nausea and vomiting
- Ectopic beats (arrhythmias)
- Tachycardia
- Palpitations
- Hypotension (at low doses) or Hypertension (at high doses)
- Dyspnea
- Vasoconstriction (reduced peripheral circulation)
- Severe tissue necrosis and sloughing (if extravasated)
注意事項與禁忌
- Pheochromocytoma
- Ventricular fibrillation
- Uncorrected tachyarrhythmias
- Uncorrected hypovolemia (must replace fluids first)
- ### Critical Warnings * **Extravasation Risk**: Extravasation can cause severe ischemic tissue necrosis and sloughing. Monitor IV sites continuously. If extravasation occurs, infiltrate the ischemic area with 5-10 mg **phentolamine** diluted in 10-15 mL of normal saline using a fine needle with multiple subcutaneous injections. * **Hypovolemia**: Dopamine is *not* a substitute for adequate fluid, electrolyte, or blood product replacement. Volume deficits must be corrected prior to use. * **Cardiovascular Disease**: Use with extreme caution in patients with ischemic heart disease or occlusive vascular disease. Discontinue or reduce dose if arrhythmias (e.g., PVCs) occur or if signs of reduced peripheral circulation develop. * **Feline Renal Failure**: Cats are unlikely to benefit from low-dose dopamine for oliguric renal failure, and it may be detrimental.
藥物相互作用
- Alpha-adrenergic blockers (e.g., prazosin): May antagonize the vasoconstrictive properties of high-dose dopamine.
- Halogenated hydrocarbon anesthetics (e.g., halothane): May result in increased incidences of ventricular arrhythmias.
- Tricyclic antidepressants: May potentiate adverse cardiovascular effects.
- Beta-blockers (e.g., propranolol, metoprolol): May antagonize the cardiac (inotropic/chronotropic) effects of dopamine.
- Diuretics: May potentiate urine production effects of low-dose dopamine.
- Monoamine oxidase inhibitors (MAOIs): Can significantly prolong and enhance the effects of dopamine.
- Oxytocic drugs: May cause severe hypertension when used concurrently.
- Phenothiazines: May antagonize the renal and mesenteric vasodilatation effects of dopamine.
- Vasopressors/Vasoconstrictors: Concurrent use may cause severe hypertension.
常見問題
Dopamine用於寵物有甚麼用途？
Dopamine is a critical care medication used exclusively in a hospital setting, typically in an Intensive Care Unit (ICU). * **Purpose**: It is used to support your pet's blood pressure, heart function, and organ blood flow during life-threatening conditions like severe shock or heart failure. * **Administration**: It is given as a continuous intravenous (IV) drip using a specialized pump to ensure exact dosing. * **Monitoring**: While on this medication, your pet will be closely monitored by the veterinary team, including continuous heart rate, ECG, and blood pressure checks. * **Safety**: The veterinary team will frequently check the IV catheter, as this medication can cause tissue damage if it leaks outside the vein.
Dopamine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。