Desmopressin
別名: Stimate, DDAVP, Concentraid, D-Void, Defirin, Desmogalen, Desmospray, Desmotabs, Emosint, Minirin, Minurin, Nocutil, Octim, Octostim, Presinex
- **Administration Technique:** For diabetes insipidus, you will likely be instructed to place drops of the human *nasal spray* directly into your pet's eye (conjunctival sac). This is normal and is the most effective way for pets to absorb the medication. - **Storage:** Keep the solution refrigerated (2-8°C) whenever possible to maintain its effectiveness. - **Lifelong Therapy:** Understand that for central diabetes insipidus, this medication is a *treatment*, not a cure. Strict compliance with the daily dosing schedule is essential to prevent your pet from experiencing severe thirst and excessive urination. - **Cost:** This medication can be expensive for long-term use; discuss any financial concerns with your veterinarian. - **Water Intake:** Ensure your pet always has access to water, but monitor for signs of lethargy or weakness, which could indicate water intoxication if the dose is too high.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Differentiate central diabetes insipidus from nephrogenic form
- Central diabetes insipidus
- Central diabetes insipidus
- Central diabetes insipidus
- Central diabetes insipidus (oral alternative)
- Diagnosis of diabetes insipidus
- Diagnosis of diabetes insipidus
- Central diabetes insipidus
- Central diabetes insipidus
- Central diabetes insipidus
- Complete and partial central diabetes insipidus
- Central diabetes insipidus
- Trial in place of water deprivation test
給藥方式
可能的副作用
- Eye irritation (following conjunctival administration)
- Hypersensitivity reactions
- Fluid retention (with overdosage)
- Hyponatremia (with overdosage)
- Headache (reported in humans)
注意事項與禁忌
- Hypersensitivity to desmopressin
- Type IIB or platelet-type (pseudo) Von Willebrand's disease (may cause platelet aggregation and thrombocytopenia; notably seen in German Shorthair Pointers)
- Hyponatraemia (specifically for modified water deprivation test)
- Renal disease (specifically for modified water deprivation test)
- Dehydration (specifically for modified water deprivation test)
- Hypercalcaemia (specifically for modified water deprivation test)
- Use with extreme caution in patients susceptible to thrombotic events. When used to stimulate von Willebrand factor, repeated administration will cause tachyphylaxis (diminishing efficacy) within 24 hours. Safe use during pregnancy is not fully established (FDA Category B), though animal studies at high doses showed no fetal harm. Likely safe during nursing.
藥物相互作用
- Chlorpropamide: May enhance the antidiuretic effects of desmopressin
- Fludrocortisone: May enhance the antidiuretic effects of desmopressin
- Urea: May enhance the antidiuretic effects of desmopressin
常見問題
Desmopressin用於寵物有甚麼用途？
- **Administration Technique:** For diabetes insipidus, you will likely be instructed to place drops of the human *nasal spray* directly into your pet's eye (conjunctival sac). This is normal and is the most effective way for pets to absorb the medication. - **Storage:** Keep the solution refrigerated (2-8°C) whenever possible to maintain its effectiveness. - **Lifelong Therapy:** Understand that for central diabetes insipidus, this medication is a *treatment*, not a cure. Strict compliance with the daily dosing schedule is essential to prevent your pet from experiencing severe thirst and excessive urination. - **Cost:** This medication can be expensive for long-term use; discuss any financial concerns with your veterinarian. - **Water Intake:** Ensure your pet always has access to water, but monitor for signs of lethargy or weakness, which could indicate water intoxication if the dose is too high.
Desmopressin對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。